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埃塞俄比亚奥罗米亚比绍夫图综合医院新生儿先天性畸形及相关因素的回顾性研究。

Congenital Anomalies and Associated Factors among Newborns in Bishoftu General Hospital, Oromia, Ethiopia: A Retrospective Study.

机构信息

Department of Midwifery, College of Health Sciences, Assosa University, Assosa, Ethiopia.

School of Nursing and Midwifery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

J Environ Public Health. 2021 Mar 31;2021:2426891. doi: 10.1155/2021/2426891. eCollection 2021.

Abstract

BACKGROUND

Congenital anomalies affect millions of babies worldwide with prevalence of 3%, and it is estimated that, globally, 303,000 newborns die within the first 4 weeks of life due to this problem.

OBJECTIVE

This study aimed to assess congenital anomalies and their associated factors among newborns in Bishoftu General Hospital, Oromia Regional State, Ethiopia. . Bishoftu General Hospital, Oromia, Ethiopia. . A retrospective cross-sectional study was employed. . All birth records from September 14, 2018, to March 14, 2019, were reviewed. A census method was applied for this study. The data were collected from birth registration books through structured checklist. We used Statistical Package for the Social Sciences (SPSS) version 24.0 for data analysis. Crude and adjusted odds ratio with 95% confidence interval was computed. Statistical significance was set at  < 0.05.

RESULT

Out of 2,218 live births, 23 newborns were diagnosed with congenital malformations, making the prevalence rate of 1% (i.e., 10/1000 live births in the specified time period). Maternal age above 35 years (AOR = 6.5; 95% CI = 2.4-18), birth order above 3 (AOR = 8.4; 95% CI = 3.4-20.7), birth weight less than 2.5 kg (AOR = 0.3; 95% CI = 0.1-0.9), and singleton pregnancy (AOR = 6.4; 95% CI = 2-18.9) had a significant association with the incident of congenital anomalies, while iron folate use before and/or during early pregnancy and urban residence (AOR = 0.3; 95% CI = 0.1-1) had a protective effect against congenital anomalies (AOR = 0.036; 95% CI = 0.008-0.15).

CONCLUSION

The findings of this study showed that there is a burden of congenital anomalies in the study area. Sustainable surveillance and registry systems are thus required for intervention programs and it is crucial to include them under Ethiopian demographic health survey (EDHS) report.

摘要

背景

先天性异常影响着全球数以百万计的婴儿,其患病率为 3%,据估计,在全球范围内,有 30.3 万名新生儿在生命的头 4 周内死亡,原因是这个问题。

目的

本研究旨在评估埃塞俄比亚奥罗米亚州比绍夫图综合医院新生儿的先天性异常及其相关因素。

地点

埃塞俄比亚奥罗米亚州比绍夫图综合医院。

方法

这是一项回顾性的横断面研究。研究对象为 2018 年 9 月 14 日至 2019 年 3 月 14 日期间的所有分娩记录。采用普查法进行本项研究。数据通过结构化检查表从出生登记册中收集。我们使用社会科学统计软件包(SPSS)第 24.0 版进行数据分析。采用粗比值比(OR)和 95%置信区间(CI)进行分析。统计显著性设定为  < 0.05。

结果

在 2218 例活产儿中,有 23 例新生儿被诊断为先天性畸形,患病率为 1%(即特定时期每 1000 例活产儿中有 10 例)。母亲年龄大于 35 岁(OR=6.5;95%CI=2.4-18)、产次大于 3(OR=8.4;95%CI=3.4-20.7)、出生体重小于 2.5kg(OR=0.3;95%CI=0.1-0.9)和单胎妊娠(OR=6.4;95%CI=2-18.9)与先天性异常的发生有显著关联,而在妊娠早期使用铁叶酸以及城市居住(OR=0.3;95%CI=0.1-1)与先天性异常有保护作用(OR=0.036;95%CI=0.008-0.15)。

结论

本研究结果表明,该研究地区存在先天性异常负担。因此,需要建立可持续的监测和登记系统,并将其纳入埃塞俄比亚人口健康调查(EDHS)报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d035/8026314/4bdc666be773/JEPH2021-2426891.001.jpg

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