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新冠疫情时代的前列腺癌管理:来自香港泌尿外科学会和香港泌尿肿瘤学会的建议。

Prostate cancer management in the era of COVID-19: Recommendations from the Hong Kong Urological Association and Hong Kong Society of Uro-oncology.

机构信息

Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Sha Tin, Hong Kong.

Comprehensive Oncology Centre, Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong.

出版信息

Asia Pac J Clin Oncol. 2021 Apr;17 Suppl 3(Suppl 3):48-54. doi: 10.1111/ajco.13579.

Abstract

AIM

In response to the fast-developing coronavirus disease 2019 (COVID-19) pandemic, special arrangement and coordination are urgently required in the interdisciplinary care of patients across different medical specialties. This article provides recommendations on the management of different stages of localized or metastatic prostate cancer (PC) amid this pandemic.

METHODS

The Hong Kong Urological Association and Hong Kong Society of Uro-oncology formed a joint discussion panel, which consisted of six urologists and six clinical oncologists with extensive experience in the public and private sectors. Following an evidence-based approach, the latest relevant publications were searched and reviewed, before proceeding to a structured discussion of relevant clinical issues.

RESULTS

The joint panel provided recommendations for PC management during the pandemic, in terms of general considerations, diagnostic procedures, different disease stages, treatment modules, patient support, and interdisciplinary collaboration. The overall goal was to minimize the risk of infection while avoiding unnecessary delays and compromises in management outcomes. Practical issues during the pandemic were addressed such as the use of invasive diagnostic procedures, robotic-assisted laparoscopic prostatectomy, hypofractionated radiotherapy, and prolonged androgen deprivation therapy. The recommendations were explicated in the context of Hong Kong, a highly populated international city, in relation to the latest international guidelines and evidence.

CONCLUSION

A range of recommendations on the management of PC patients during the COVID-19 pandemic was developed. Urologists, oncologists, and physicians treating PC patients may refer to them as practical guidance.

摘要

目的

针对快速发展的 2019 年冠状病毒病(COVID-19)大流行,需要在不同医学专业的患者跨学科护理方面进行特别的安排和协调。本文提供了在大流行期间管理局部或转移性前列腺癌(PC)不同阶段的建议。

方法

香港泌尿科协会和香港肿瘤泌尿学会组成了一个联合讨论小组,由六名泌尿科医生和六名在公共和私营部门拥有丰富经验的临床肿瘤学家组成。该小组采用循证方法,搜索和回顾了最新的相关出版物,然后对相关临床问题进行了结构化讨论。

结果

联合小组就大流行期间的 PC 管理提供了建议,包括一般注意事项、诊断程序、不同疾病阶段、治疗模块、患者支持和跨学科合作。总体目标是在避免管理结果不必要的延迟和妥协的同时,将感染风险降到最低。针对大流行期间的实际问题,例如使用侵入性诊断程序、机器人辅助腹腔镜前列腺切除术、低分割放疗和延长雄激素剥夺疗法。这些建议是在与最新的国际指南和证据相关的情况下,针对人口稠密的国际城市香港的具体情况进行阐述的。

结论

制定了一系列关于 COVID-19 大流行期间 PC 患者管理的建议。治疗 PC 患者的泌尿科医生、肿瘤学家和内科医生可以将这些建议作为实用指南。

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Airborne transmission of SARS-CoV-2: The world should face the reality.空气传播 SARS-CoV-2:全世界应正视现实。
Environ Int. 2020 Jun;139:105730. doi: 10.1016/j.envint.2020.105730. Epub 2020 Apr 10.
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Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19.应对2019冠状病毒病的前列腺癌放射治疗建议
Adv Radiat Oncol. 2020 Apr 1;5(4):659-665. doi: 10.1016/j.adro.2020.03.010. eCollection 2020 Jul-Aug.
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COVID-19 and urology: a comprehensive review of the literature.COVID-19 与泌尿科:文献综述
BJU Int. 2020 Jun;125(6):E7-E14. doi: 10.1111/bju.15071. Epub 2020 May 12.

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