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经口机器人手术治疗阻塞性睡眠呼吸暂停综合征的手术、临床和功能结局:系统评价和荟萃分析。

Surgical, clinical, and functional outcomes of transoral robotic surgery used in sleep surgery for obstructive sleep apnea syndrome: A systematic review and meta-analysis.

机构信息

Research Committee, Robotic Surgery Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France.

Department of Human Anatomy and Experimental Oncology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

出版信息

Head Neck. 2021 Jul;43(7):2216-2239. doi: 10.1002/hed.26702. Epub 2021 Apr 16.

DOI:10.1002/hed.26702
PMID:33860981
Abstract

We investigated safety and efficacy of transoral robotic surgery (TORS) for base of tongue (BOT) reduction in obstructive sleep apnea syndrome (OSAS) patients. PubMed, Cochrane Library, and Scopus were searched. A meta-analysis was performed. Random effects models were used. Thirty-one cohorts met our criteria (1693 patients). The analysis was based mostly on retrospective studies. The summary estimate of the reduction of Apnea-Hypoxia Index (AHI) was 24.25 abnormal events per hour (95% CI: 21.69-26.81) and reduction of Epworth Sleepiness Scale (ESS) was 7.92 (95% CI: 6.50-9.34). The summary estimate of increase in lowest O saturation was 6.04% (95% CI: 3.05-9.03). The success rate of TORS BOT reduction, either alone or combined with other procedures, was 69% (95% CI: 64-79). The majority of studies reported low level of evidence but suggested that TORS BOT reduction may be a safe procedure associated with improvement of AHI, ESS, and lowest O saturation.

摘要

我们研究了经口机器人手术(TORS)治疗阻塞性睡眠呼吸暂停综合征(OSAS)患者舌根(BOT)缩小的安全性和有效性。我们检索了 PubMed、Cochrane Library 和 Scopus。进行了荟萃分析。使用随机效应模型。31 项研究符合我们的标准(1693 名患者)。该分析主要基于回顾性研究。呼吸暂停-低通气指数(AHI)减少的综合估计值为 24.25 个异常事件/小时(95%CI:21.69-26.81),嗜睡量表(ESS)减少 7.92(95%CI:6.50-9.34)。最低血氧饱和度增加的综合估计值为 6.04%(95%CI:3.05-9.03)。TORS BOT 缩小术(单独或联合其他手术)的成功率为 69%(95%CI:64-79)。大多数研究报告的证据水平较低,但表明 TORS BOT 缩小术可能是一种安全的手术,可改善 AHI、ESS 和最低血氧饱和度。

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