Department of Obstetrics and Gynecology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
J Gynecol Obstet Hum Reprod. 2021 Oct;50(8):102146. doi: 10.1016/j.jogoh.2021.102146. Epub 2021 Apr 20.
Pregnancy complicated with ovarian endometrioma is a risk factor for preterm delivery and rupture or infection during pregnancy. This study aimed to clarify the effectiveness and safety of transvaginal aspiration during pregnancy for endometrioma diagnosed in the first trimester.
This retrospective observational study included 8 pregnant women with endometrioma who underwent transvaginal cyst aspiration at 12-14 weeks (aspiration group) between March 2011-March 2018 and 23 pregnant women with endometrioma who refused aspiration during the same period (observation group).
Characteristics of patients were compared in both groups. Safety, feasability and complications of transvaginal cyst aspiration were reported. Complications and obstetrical outcomes were reported and compared in both groups.
The maximum cyst diameter was 8.9 ± 1.5 cm (mean ± standard deviation) in the aspiration group, which was significantly larger than that in the observation group (4.7 ± 0.2 cm). Four preterm deliveries (17.3%) occurred in the observation group and none in the aspiration group. The emergency cesarean section rate during delivery was 14.2% in the aspiration group and 43.7% in the observation group.
The aspiration group tended to have lower rate of preterm deliveries and emergency cesarean sections, suggesting that cyst aspiration could be an effective, minimally invasive, and safe management option for endometrioma during pregnancy.
妊娠合并卵巢子宫内膜异位囊肿是早产以及妊娠期间破裂或感染的危险因素。本研究旨在阐明在妊娠 12-14 周经阴道囊肿抽吸术对于诊断为早期子宫内膜异位囊肿的有效性和安全性。
本回顾性观察研究纳入了 2011 年 3 月至 2018 年 3 月期间因患有子宫内膜异位囊肿而在 12-14 周(抽吸组)行经阴道囊肿抽吸术的 8 例孕妇和同期因拒绝抽吸而患有子宫内膜异位囊肿的 23 例孕妇(观察组)。
比较两组患者的特征。报告并比较经阴道囊肿抽吸术的安全性、可行性和并发症。报告并比较两组的并发症和产科结局。
抽吸组的最大囊肿直径为 8.9±1.5cm(平均值±标准差),明显大于观察组的 4.7±0.2cm。观察组中有 4 例(17.3%)早产,而抽吸组中没有。抽吸组的紧急剖宫产率为 14.2%,观察组为 43.7%。
抽吸组早产和紧急剖宫产的发生率较低,提示囊肿抽吸术可能是妊娠期间子宫内膜异位囊肿的一种有效、微创且安全的治疗选择。