Emory Global Diabetes Research Center, Hubert Department of Global Health, Rollins School of Global Health, Emory University, Atlanta, GA
Emory Global Diabetes Research Center, Hubert Department of Global Health, Rollins School of Global Health, Emory University, Atlanta, GA.
Diabetes Care. 2021 Jun;44(6):1264-1272. doi: 10.2337/dc20-2652. Epub 2021 Apr 16.
We investigated the risk of depression and anxiety in people whose spouse did or did not have diabetes. We also examined associations between depression and anxiety and severity of spouse's diabetes.
We analyzed prospective self-reported data about diagnosed depression/anxiety and diabetes in cohabiting couples in the national Panel Study of Income Dynamics (PSID) during 1999-2017 ( = 13,500, 128,833 person-years of follow-up, median follow-up 8.1 years). We used Poisson models to estimate incidence and incidence rate ratios (IRRs) of depression/anxiety, according to spouse's diabetes status overall and by severity of diabetes.
Age-, sex-, and race-adjusted incidence of depression/anxiety was 8.0/1,000 person-years (95% CI 6.5, 9.6) among those whose spouse had diabetes and 6.5/1,000 person-years (95% CI 6.0, 6.9) among those whose spouse did not have diabetes. Those whose spouse had diabetes had higher risk of depression/anxiety (IRR 1.24 [95% CI 1.01, 1.53]). Those whose spouse had diabetes-related limitations in daily activities (IRR 1.89 [95% CI 1.35, 2.67]) and diabetes combined with other chronic conditions (IRR 2.34 [95% CI 1.78, 3.09]) were more likely to develop depression/anxiety, while those whose spouse had diabetes with no limitations or additional chronic conditions had incidence of depression/anxiety similar to that of subjects whose spouses did not have diabetes.
People living with a spouse with diabetes are at higher risk of developing depression/anxiety than people whose spouse does not have diabetes; this risk is driven by the severity of the spouse's diabetes. Strategies to address the impacts of diabetes on families need to be devised and tested.
我们调查了配偶患有或未患糖尿病的人患抑郁和焦虑的风险。我们还研究了配偶糖尿病严重程度与抑郁和焦虑之间的关系。
我们分析了 1999 年至 2017 年全国收入动态小组研究（PSID）中同居夫妇的自我报告诊断为抑郁/焦虑和糖尿病的前瞻性数据（=13500，128833 人年随访，中位数随访 8.1 年）。我们使用泊松模型根据配偶的糖尿病状况（总体和严重程度）估计抑郁/焦虑的发病率和发病率比（IRR）。
年龄、性别和种族调整后的抑郁/焦虑发生率为配偶患有糖尿病的人群中为 8.0/1000 人年（95%CI 6.5，9.6），配偶未患有糖尿病的人群中为 6.5/1000 人年（95%CI 6.0，6.9）。配偶患有糖尿病的人患抑郁/焦虑的风险更高（IRR 1.24 [95%CI 1.01，1.53]）。那些配偶患有糖尿病相关日常生活活动受限（IRR 1.89 [95%CI 1.35，2.67]）和糖尿病合并其他慢性疾病（IRR 2.34 [95%CI 1.78，3.09]）的人更有可能患上抑郁/焦虑症，而那些配偶患有糖尿病且无任何限制或其他慢性疾病的人患抑郁/焦虑症的发生率与配偶未患有糖尿病的人相似。
与配偶没有糖尿病的人相比，与患有糖尿病的配偶生活在一起的人患抑郁/焦虑的风险更高；这种风险是由配偶糖尿病的严重程度驱动的。需要制定和测试针对糖尿病对家庭影响的策略。
