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血尿待查?想到这些罕见病因……

Haematuria without diagnosis? Think about the rare causes….

机构信息

Department of Paediatrics, Centro Hospitalar do Oeste, Unidade de Caldas da Rainha, Caldas da Rainha, Portugal

Department of Imaging, Centro Hospitalar do Oeste, Unidade de Caldas da Rainha, Caldas da Rainha, Portugal.

出版信息

BMJ Case Rep. 2021 Apr 16;14(4):e240228. doi: 10.1136/bcr-2020-240228.

DOI:10.1136/bcr-2020-240228
PMID:33863767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8055149/
Abstract

We describe a case of a 17-year-old man admitted in the emergency room with a 2-month history of intermittent macroscopic haematuria and left lumbar pain. Physical examination and vital signs were normal. Investigation indicated a recurrent non-glomerular haematuria. The Doppler ultrasound revealed a compression of the left renal vein with upstream dilatation which was subsequently confirmed by CT angiography. These findings are in keeping with a case of nutcracker syndrome (NutS). Although asymptomatic in most cases, it can be a rare cause of haematuria. The teenager was referred to paediatric nephrology and was treated conservatively with spontaneous resolution of macroscopic haematuria. With this case, we would like to highlight that in children or adolescents with haematuria without an apparent cause, a high level of suspicion and appropriate imaging are necessary for the diagnosis of NutS.

摘要

我们描述了一例 17 岁男性患者因间歇性肉眼血尿和左侧腰痛就诊于急诊室,病史 2 个月。体格检查和生命体征正常。检查提示复发性非肾小球性血尿。多普勒超声显示左肾静脉受压,上游扩张,随后 CT 血管造影证实。这些发现符合胡桃夹综合征(NutS)。虽然大多数情况下无症状,但血尿少见。该青少年被转至儿科肾病科,并接受保守治疗,肉眼血尿自发缓解。通过本病例,我们想强调,对于无明显病因的血尿儿童或青少年,应高度怀疑并进行适当的影像学检查以诊断 NutS。

相似文献

1
Haematuria without diagnosis? Think about the rare causes….血尿待查?想到这些罕见病因……
BMJ Case Rep. 2021 Apr 16;14(4):e240228. doi: 10.1136/bcr-2020-240228.
2
Haematuria and the retro-aortic left renal vein.血尿与主动脉后左肾静脉
BMJ Case Rep. 2012 Aug 27;2012:bcr0220125836. doi: 10.1136/bcr.02.2012.5836.
3
[Macroscopic hematuria secondary to nutcracker syndrome and successful endovascular treatment].胡桃夹综合征继发肉眼血尿及成功的血管内治疗
Cir Cir. 2017 Dec;85 Suppl 1:19-25. doi: 10.1016/j.circir.2016.11.015. Epub 2016 Dec 28.
4
Left renal vein entrapment syndrome: nutcracker syndrome!左肾静脉受压综合征:胡桃夹综合征!
BMJ Case Rep. 2019 Sep 4;12(9):e230877. doi: 10.1136/bcr-2019-230877.
5
[Nutcracker syndrome].[胡桃夹综合征]
Medicina (B Aires). 2019;79(2):150-153.
6
A rare cause of recurrent hematuria in children: Nutcracker syndrome.儿童复发性血尿的罕见病因:胡桃夹综合征。
J Trop Pediatr. 2010 Aug;56(4):275-7. doi: 10.1093/tropej/fmp121. Epub 2009 Dec 10.
7
Adolescent with intermittent haematuria.
Arch Dis Child Educ Pract Ed. 2019 Jun;104(3):157-159. doi: 10.1136/archdischild-2018-315049. Epub 2018 May 10.
8
Cracking haematuria in adolescent with negative work up.检查结果为阴性的青少年血尿症
BMJ Case Rep. 2013 May 24;2013:bcr2013009924. doi: 10.1136/bcr-2013-009924.
9
A case report of a young girl with recurrent hematuria: a missed diagnosis - renal nutcracker syndrome.年轻女孩反复血尿病例报告:漏诊-胡桃夹综合征。
BMC Nephrol. 2019 Sep 5;20(1):349. doi: 10.1186/s12882-019-1508-6.
10
Posterior nutcracker syndrome.胡桃夹综合征(又称左肾静脉受压综合征),是指左肾静脉在回流入下腔静脉过程中在穿经腹主动脉和肠系膜上动脉之间的夹角时受到挤压,而引起的一系列临床症状。 胡桃夹综合征(又称左肾静脉受压综合征),是指左肾静脉在回流入下腔静脉过程中在穿经腹主动脉和肠系膜上动脉之间的夹角时受到挤压,而引起的一系列临床症状。 需要注意的是,你提供的原文“Posterior nutcracker syndrome”表述有误,正确的应该是“Posterior nutcracker phenomenon”,其准确的中文是“胡桃夹现象”,更为准确的译文是: 胡桃夹现象。
Vasc Endovascular Surg. 2011 Nov;45(8):749-55. doi: 10.1177/1538574411419376. Epub 2011 Sep 2.

本文引用的文献

1
A case report of a young girl with recurrent hematuria: a missed diagnosis - renal nutcracker syndrome.年轻女孩反复血尿病例报告:漏诊-胡桃夹综合征。
BMC Nephrol. 2019 Sep 5;20(1):349. doi: 10.1186/s12882-019-1508-6.
2
Diagnosis and treatment of the Nutcracker syndrome: a review of the last 10 years.胡桃夹综合征的诊断与治疗:过去10年综述
J Vasc Bras. 2018 Jul-Sep;17(3):220-228. doi: 10.1590/1677-5449.012417.
3
Nutcracker Syndrome in Children: Role of Doppler Ultrasonographic Indices in Detecting the Pattern of Symptoms.儿童胡桃夹综合征:多普勒超声指标在检测症状模式中的作用。
J Clin Med. 2018 Aug 13;7(8):214. doi: 10.3390/jcm7080214.
4
What Each Clinical Anatomist Has to Know about Left Renal Vein Entrapment Syndrome (Nutcracker Syndrome): A Review of the Most Important Findings.每个临床解剖学家都必须了解的左肾静脉压迫综合征(胡桃夹综合征):最重要发现的综述。
Biomed Res Int. 2017;2017:1746570. doi: 10.1155/2017/1746570. Epub 2017 Dec 11.
5
Nutcracker syndrome--how well do we know it?胡桃夹综合征——我们了解多少?
Urology. 2014 Jan;83(1):12-7. doi: 10.1016/j.urology.2013.08.033. Epub 2013 Oct 18.
6
Clinical course of children with nutcracker syndrome.儿童胡桃夹综合征的临床病程。
Urology. 2013 Sep;82(3):686-90. doi: 10.1016/j.urology.2013.03.048. Epub 2013 Jun 2.
7
A rare cause of recurrent hematuria in children: Nutcracker syndrome.儿童复发性血尿的罕见病因:胡桃夹综合征。
J Trop Pediatr. 2010 Aug;56(4):275-7. doi: 10.1093/tropej/fmp121. Epub 2009 Dec 10.