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临床预测是预防个体女性分娩创伤和盆底功能障碍的核心。

Clinical prediction is at the heart of preventing birth trauma and pelvic floor disorders for individual women.

机构信息

Department of Obstetrics & Gynecology, Duke University School of Medicine, DUMC 3084, Durham, NC, 27710, USA.

出版信息

Int Urogynecol J. 2021 Jul;32(7):1971-1976. doi: 10.1007/s00192-021-04797-9. Epub 2021 Apr 17.

DOI:10.1007/s00192-021-04797-9
PMID:33864475
Abstract

INTRODUCTION AND HYPOTHESIS

The purpose of this article is to understand that the majority of studies investigating the role of risk factors for maternal birth trauma and pelvic floor disorders are designed using causal inferential statistical methods and have not been designed to investigate the more useful goal of clinical prediction.

METHODS

A review of the literature was conducted to describe notable causal and predictive associations between risk factors and maternal birth trauma outcomes. Examples were obtained to illustrate and contrast differences in clinical usefulness between causal and predictive models.

RESULTS

Effects of pregnancy and childbirth on the risk of maternal birth trauma outcomes and subsequent pelvic floor disorders are an area of profound investigation. Numerous observational studies provide evidence that pregnancy and childbirth play a causal role in the increasing prevalence of these outcomes, and clinicians must rely on this observational evidence to guide decisions about preventing maternal birth trauma and pelvic floor disorders. However, there are important differences between the design and evaluation of models for a predictive context including: study design goals, inclusion or exclusion of candidate risk factors, model evaluation and the additional need to assess model error.

CONCLUSION

This article contrasts how causal and predictive modeling approaches are different and argues that indiscriminately modeling risk factors for birth trauma and pelvic floor disorder outcomes is costly to women.

摘要

引言与假设

本文旨在了解大多数研究调查产妇分娩创伤和盆底功能障碍风险因素的作用是使用因果推理统计方法设计的,而不是为了研究更有用的临床预测目标。

方法

对文献进行综述,以描述风险因素与产妇分娩创伤结局之间的显著因果和预测关联。举例说明了因果和预测模型在临床实用性方面的差异。

结果

妊娠和分娩对产妇分娩创伤结局和随后的盆底功能障碍的影响是一个深入研究的领域。许多观察性研究提供了证据,证明妊娠和分娩在这些结局的患病率增加中起着因果作用,临床医生必须依赖这一观察性证据来指导预防产妇分娩创伤和盆底功能障碍的决策。然而,预测性背景下模型的设计和评估之间存在重要差异,包括:研究设计目标、候选风险因素的纳入或排除、模型评估以及额外需要评估模型误差。

结论

本文对比了因果和预测建模方法的不同之处,并认为对分娩创伤和盆底功能障碍结局的风险因素进行不加区分的建模对女性来说代价高昂。

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引用本文的文献

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本文引用的文献

1
A Framework for the Evaluation of Statistical Prediction Models.统计预测模型评估框架。
Chest. 2020 Jul;158(1S):S29-S38. doi: 10.1016/j.chest.2020.03.005.
2
Risk factors for severe perineal trauma during childbirth: An updated meta-analysis.分娩期间严重会阴创伤的危险因素:一项更新的荟萃分析。
Eur J Obstet Gynecol Reprod Biol. 2020 Apr;247:94-100. doi: 10.1016/j.ejogrb.2020.02.025. Epub 2020 Feb 14.
3
Association of Delivery Mode With Pelvic Floor Disorders After Childbirth.分娩方式与产后盆底功能障碍的关系。
JAMA. 2018 Dec 18;320(23):2438-2447. doi: 10.1001/jama.2018.18315.
4
Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis.剖宫产术对母婴及后续妊娠的长期风险和获益:系统评价和荟萃分析。
PLoS Med. 2018 Jan 23;15(1):e1002494. doi: 10.1371/journal.pmed.1002494. eCollection 2018 Jan.
5
Risk Factors for the Development of Obstetric Anal Sphincter Injuries in Modern Obstetric Practice.现代产科实践中产科肛门括约肌损伤的危险因素。
Obstet Gynecol. 2018 Feb;131(2):290-296. doi: 10.1097/AOG.0000000000002444.
6
Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD).个体预后或诊断多变量预测模型的透明报告(TRIPOD)。
Ann Intern Med. 2015 May 19;162(10):735-6. doi: 10.7326/L15-5093-2.
7
Prediction models for postpartum urinary and fecal incontinence in primiparous women.初产妇产后尿失禁和粪失禁的预测模型
Female Pelvic Med Reconstr Surg. 2013 Mar-Apr;19(2):110-8. doi: 10.1097/SPV.0b013e31828508f0.
8
Prevalence and risk factors for pelvic organ prolapse 20 years after childbirth: a national cohort study in singleton primiparae after vaginal or caesarean delivery.产后 20 年盆腔器官脱垂的患病率及危险因素:阴道分娩或剖宫产分娩后单胎初产妇的全国队列研究。
BJOG. 2013 Jan;120(2):152-160. doi: 10.1111/1471-0528.12020. Epub 2012 Nov 2.
9
The prevalence of urinary incontinence 20 years after childbirth: a national cohort study in singleton primiparae after vaginal or caesarean delivery.产后 20 年尿失禁的患病率:阴道分娩或剖宫产分娩后单胎初产妇的全国队列研究。
BJOG. 2013 Jan;120(2):144-151. doi: 10.1111/j.1471-0528.2012.03301.x. Epub 2012 Mar 14.
10
Effect of mode of delivery on the incidence of urinary incontinence in primiparous women.分娩方式对初产妇尿失禁发生率的影响。
Obstet Gynecol. 2009 Jan;113(1):134-141. doi: 10.1097/AOG.0b013e318191bb37.