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针对抑郁症患者的基于社区的多地点行为激活随机对照试验。

Community-Based Multi-Site Randomized Controlled Trial of Behavioral Activation for Patients with Depressive Disorders.

作者信息

Lee Eunbyeol, Han Yeoul, Cha Yun Ji, Oh Ji-Hye, Hwang Na-Ri, Seo Ho-Jun, Choi Kee-Hong

机构信息

Department of Psychology, Korea University, 145, Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.

Department of Psychiatry, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, 93, Jungbu-daero, Paldal-gu, Suwon-si, Gyeonggi-do, 16247, Republic of Korea.

出版信息

Community Ment Health J. 2022 Feb;58(2):343-355. doi: 10.1007/s10597-021-00828-3. Epub 2021 Apr 17.

DOI:10.1007/s10597-021-00828-3
PMID:33864548
Abstract

Behavioral activation (BA) is a beneficial and relatively cost-effective treatment option for depression. This study utilized a pragmatic randomized controlled research design to investigate whether BA, as compared with treatment as usual (TAU), led to superior treatment effects, when delivered in community mental health settings by retrained community mental health professionals. Patients with depressive disorders (n = 64) were randomly assigned to a 10-session BA (n = 31) or TAU (n = 33) group. The depressive symptoms and behavioral engagement were assessed at the baseline, post-treatment, and a six-month follow-up. Results showed that, as compared to the TAU group, the BA group had: (1) a reduction in depression severity, as evidenced by large effect sizes and greater response rates, and (2) an increase in behavioral engagement. However, the post-treatment gains were not maintained at the six-month follow-up. The implications and limitations of the study are also discussed (KCT0004098, June 27, 2019, retrospectively registered).

摘要

行为激活疗法(BA)是一种治疗抑郁症的有效且相对经济高效的方法。本研究采用实用随机对照研究设计,以调查在社区心理健康环境中由重新培训的社区心理健康专业人员实施时,与常规治疗(TAU)相比,行为激活疗法是否能带来更优的治疗效果。患有抑郁症的患者(n = 64)被随机分配至为期10节的行为激活疗法组(n = 31)或常规治疗组(n = 33)。在基线、治疗后及六个月随访时评估抑郁症状和行为参与度。结果显示,与常规治疗组相比,行为激活疗法组有:(1)抑郁严重程度降低,表现为效应量较大和缓解率更高;(2)行为参与度增加。然而,治疗后的改善在六个月随访时未得到维持。本研究的意义和局限性也进行了讨论(KCT0004098,2019年6月27日,回顾性注册)。

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Behav Ther. 2019 Sep;50(5):864-885. doi: 10.1016/j.beth.2019.01.003. Epub 2019 Jan 29.
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