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一种用于在超声心动图像中自动识别人工二尖瓣的深度学习方法。

A deep learning approach for the automatic recognition of prosthetic mitral valve in echocardiographic images.

机构信息

Biomedical Engineering Department, Iran University of Science and Technology, Tehran, Iran.

Biomedical Engineering Department, Iran University of Science and Technology, Tehran, Iran.

出版信息

Comput Biol Med. 2021 Jun;133:104388. doi: 10.1016/j.compbiomed.2021.104388. Epub 2021 Apr 14.

DOI:10.1016/j.compbiomed.2021.104388
PMID:33864972
Abstract

The first step in the automatic evaluation of the cardiac prosthetic valve is the recognition of such valves in echocardiographic images. This research surveyed whether a deep convolutional neural network (DCNN) could improve the recognition of prosthetic mitral valve in conventional 2D echocardiographic images. An efficient intervention to decrease the misreading rate of the prosthetic mitral valve is required for non-expert cardiologists. This intervention could serve as a section of a fully-automated analysis chain, alleviate the cardiologist's workload, and improve precision and time management, especially in an emergent situation. Additionally, it might be suitable for pre-labeling large databases of unclassified images. We, therefore, introduce a large publicly-available annotated dataset for the purpose of prosthetic mitral valve recognition. We utilized 2044 comprehensive non-stress transthoracic echocardiographic studies. Totally, 1597 patients had natural mitral valves and 447 patients had prosthetic valves. Each case contained 1 cycle of echocardiographic images from the apical 4-chamber (A4C) and the parasternal long-axis (PLA) views. Thirteen versions of the state-of-the-art models were independently trained, and the ensemble predictions were performed using those versions. For the recognition of prosthetic mitral valves from natural mitral valves, the area under the receiver-operating characteristic curve (AUC) made by the deep learning algorithm was similar to that made by cardiologists (0.99). In this research, EfficientNetB3 architecture in the A4C view and the EfficientNetB4 architecture in the PLA view were the best models among the other pre-trained DCNN models.

摘要

心脏人工瓣膜的自动评估的第一步是识别超声心动图图像中的此类瓣膜。本研究调查了深度卷积神经网络 (DCNN) 是否可以提高对常规 2D 超声心动图图像中人工二尖瓣的识别能力。对于非专家心脏病学家来说,需要采取有效的干预措施来降低人工二尖瓣的误读率。这种干预措施可以作为全自动分析链的一部分,减轻心脏病学家的工作量,并提高精度和时间管理能力,尤其是在紧急情况下。此外,它可能适合于对未分类的大型图像数据库进行预标记。因此,我们引入了一个大型公共标注数据集,用于人工二尖瓣识别。我们利用了 2044 项全面的非压力经胸超声心动图研究。总共,1597 名患者具有天然二尖瓣,447 名患者具有人工瓣膜。每个病例包含来自心尖 4 腔(A4C)和胸骨旁长轴(PLA)视图的 1 个心动周期的超声心动图图像。13 个版本的最先进模型被独立训练,并且使用这些版本进行集成预测。对于从天然二尖瓣中识别人工二尖瓣,深度学习算法绘制的接收器工作特征曲线(ROC)下面积(AUC)与心脏病学家绘制的 AUC 相似(0.99)。在本研究中,在 A4C 视图中使用 EfficientNetB3 架构,在 PLA 视图中使用 EfficientNetB4 架构,是其他预训练 DCNN 模型中最好的模型。

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