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未编辑的1H核磁共振乳酸/ N - 乙酰天门冬氨酸比率与脑内乳酸浓度的体内测定

Nonedited 1H NMR lactate/n-acetyl aspartate ratios and the in vivo determination of lactate concentration in brain.

作者信息

Vink R, McIntosh T K, Faden A I

机构信息

Department of Neurology, V.A. Medical Center, San Francisco, California 94121.

出版信息

Magn Reson Med. 1988 May;7(1):95-9. doi: 10.1002/mrm.1910070111.

DOI:10.1002/mrm.1910070111
PMID:3386526
Abstract

The 1H lactate/n-acetyl aspartate ratio is commonly used for the quantitation of brain lactate under pathological conditions. We demonstrate that the intensity of the lactate methyl region in water-suppressed, nonedited 1H spectra increases following mild brain trauma as a result of factors other than lactate accumulation.

摘要

1H乳酸盐/ N - 乙酰天门冬氨酸比值常用于病理条件下脑乳酸盐的定量分析。我们证明,在轻度脑外伤后,由于乳酸盐积累以外的因素,水抑制、未编辑的1H谱中乳酸盐甲基区域的强度会增加。

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