Department of Health Services and Information Management, East Carolina University, 4340E Health Sciences Building, MS 668, Greenville, NC, 27834, USA.
Department of Communication Sciences and Disorders, East Carolina University, Greenville, USA.
BMC Womens Health. 2021 Apr 17;21(1):160. doi: 10.1186/s12905-021-01305-5.
Although age specific stroke rates are higher in men, women have a higher lifetime risk and are more likely to die from a stroke. Despite this increased severity, most studies focus on male/female differences in stroke onset, patterns of care and stroke-related outcomes. Given that stroke presents differently in men and women, mixed sex studies fail to fully capture heterogeneity among women with stroke and the subsequent impact on their outcomes. This study examined the sociodemographic characteristics, factors related to stroke incidence and post-stroke functional status between young (< 60) and old (≥ 60) women with stroke.
Using 5 years of data from the National Health Interview Survey (NHIS), a nationally representative sample of US adults, cohorts of young and old women with stroke were identified. A set of demographic/lifestyle, health services utilization and health status characteristics were used evaluate within gender heterogeneity in three ways. First, disparities in population characteristics were assessed using Chi-Square and t tests. Second, young and old women with stroke were matched with women without stroke in their respective cohorts to determine differences in factors related to stroke incidence. Finally, the determinants of post-stroke functional limitation for the two cohorts were determined.
Young women with stroke were more likely to be Black, smoke regularly and frequently consume alcohol than older women. Young women were also less likely to engage with their health provider regularly or receive preventative health screenings. Diabetes, high blood pressure, high cholesterol and high BMI were correlated with an increased relative likelihood of stroke among older women. In contrast, family size, smoking frequency, alcohol consumption and sleep were correlated with an increased prevalence of stroke among young women. Although factors correlated with stroke varied between young and old women, health status and receipt of healthcare were the most significant determinants of post-stroke functional status for both cohorts.
Health related characteristics were the primary correlates of stroke in older women, whereas post-stroke lifestyle and behaviors are the most significant correlates for younger stroke survivors. These findings suggest that while receipt of health services is essential for preventing stroke in both young and old women, providers should stress the importance of post-stoke lifestyle and behaviors to younger women at risk of stroke using approaches that may be different from older stroke women.
尽管男性的特定年龄段中风发病率较高,但女性的终生风险更高,且更有可能死于中风。尽管如此,大多数研究都集中在男性/女性中风发病、护理模式和中风相关结果方面的差异。鉴于中风在男性和女性中的表现不同,混合性别研究未能充分捕捉到中风女性之间的异质性,以及这对她们的结果产生的后续影响。本研究检查了年轻(<60 岁)和老年(≥60 岁)女性中风患者的社会人口统计学特征、与中风发病率相关的因素以及中风后的功能状态。
使用美国国家健康访谈调查(NHIS)5 年的数据,这是一项美国成年人的全国代表性样本,确定了年轻和老年女性中风患者的队列。使用一套人口统计学/生活方式、卫生服务利用和健康状况特征,以三种方式评估性别内的异质性。首先,使用卡方检验和 t 检验评估人口特征差异。其次,在各自的队列中,将年轻和老年中风女性与没有中风的女性进行匹配,以确定与中风发病率相关的因素差异。最后,确定两个队列中风后功能受限的决定因素。
年轻的中风女性更有可能是黑人,经常吸烟且经常饮酒,而老年女性则较少定期与医疗服务提供者接触或接受预防性健康筛查。糖尿病、高血压、高胆固醇和高 BMI 与老年女性中风的相对可能性增加相关。相比之下,家庭规模、吸烟频率、饮酒和睡眠与年轻女性中风的患病率增加相关。尽管年轻和老年女性中风的相关因素不同,但健康状况和医疗保健的获得是两个队列中风后功能状态的最重要决定因素。
健康相关特征是老年女性中风的主要相关因素,而中风后生活方式和行为是年轻中风幸存者的最重要相关因素。这些发现表明,虽然接受卫生服务对于预防年轻和老年女性中风都很重要,但提供者应该向有中风风险的年轻女性强调中风后生活方式和行为的重要性,使用的方法可能与老年中风女性不同。