Neuroimmunology Unit, Department of Neuroscience, Hospital Alemán, Buenos Aires, Argentina.
Neuroimmunology Unit, Department of Neurology, Hospital de Clínicas "José de San Martín", Buenos Aires, Argentina.
Work. 2021;68(4):1171-1177. doi: 10.3233/WOR-213446.
Unemployment is common in people with multiple sclerosis (PwMS) and might be prevented if factors associated with work loss are identified.
We aimed to assess the impact of multiple sclerosis (MS) on employment status in a cohort of PwMS from Argentina and to evaluate their association with anxiety, depression, fatigue and disability.
A cross-sectional study was conducted to assess employment in PwMS using an anonymous, self-administered questionnaire, which also included the Hospital Anxiety and Depression Scale, Fatigue Severity Scale and Expanded Disability Status Scale. The data was compared between employed (full-time vs. part-time) vs. unemployed (looking for vs. not looking for work) PwMS. Univariate and multivariate models were designed to identify factors independently associated with unemployment.
Among the 167 PwMS, 120 (71.6%, full-time = 65%) were employed, and 47 (28.4%, looking for work = 27.6%) were currently unemployed. Age, gender, and duration of disease were similar in both groups. Univariate analysis showed that anxiety, depression, fatigue and disability were significantly associated with unemployed PwMS. However, only disability (OR = 1.36 (1.08-1.70), p = 0.007) was independently associated with unemployment after applying multivariate analysis (logistic regression).
Nearly one-third of PwMS from this sample in Argentina were unemployed. Neuropsychological factors and disability were associated with unemployment status.
多发性硬化症（MS）患者普遍存在失业问题，如果能确定与工作丧失相关的因素，或许可以预防失业。
我们旨在评估阿根廷多发性硬化症患者（PwMS）的就业状况，并评估其与焦虑、抑郁、疲劳和残疾的相关性。
采用横断面研究，通过匿名自填问卷评估 PwMS 的就业情况，问卷还包括医院焦虑抑郁量表、疲劳严重程度量表和扩展残疾状况量表。将就业的 PwMS（全职与兼职）与失业的 PwMS（正在找工作与不找工作）进行比较。设计单变量和多变量模型以确定与失业独立相关的因素。
在 167 名 PwMS 中，120 名（71.6%，全职=65%）就业，47 名（28.4%，正在找工作=27.6%）目前失业。两组的年龄、性别和疾病持续时间相似。单变量分析表明，焦虑、抑郁、疲劳和残疾与失业的 PwMS 显著相关。然而，只有残疾（OR=1.36（1.08-1.70），p=0.007）在应用多变量分析（逻辑回归）后与失业独立相关。
在阿根廷的该样本中，近三分之一的 PwMS 失业。神经心理学因素和残疾与失业状况相关。
