• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用经典猪瘟病毒2.1亚基因型分离株实验性感染猪后纽扣状溃疡的形成过程。

The formation process of button ulcers in pigs experimentally infected with a subgenotype 2.1 isolate of classical swine fever virus.

作者信息

Sudo Kasumi, Yamada Manabu, Ochiai Mariko, Iwamoto Shoko, Sakaki Hajime, Kushida Chiho, Yamashita Maiko, Yamamoto Atsushi, Nagasaka Takao, Oidemizu Mikio, Saito Akito, Yamamoto Kinya

机构信息

National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1-15-1 Tokura, Kokubunji, Tokyo 185-8511, Japan.

Present address: Food and Agriculture Organization of the United Nations, Viale delle Terme di Caracalla, 00153 Rome, Italy.

出版信息

J Vet Med Sci. 2021 Jul 10;83(6):990-993. doi: 10.1292/jvms.20-0654. Epub 2021 Apr 19.

DOI:10.1292/jvms.20-0654
PMID:33867396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8267204/
Abstract

We evaluated the role of classical swine fever virus (CSFV) in the formation of button ulcers in the mucosa of the gastrointestinal tract. Histopathological and immunohistochemical analyses of pigs experimentally infected with a subgenotype 2.1 isolate of CSFV, which was isolated in Japan in 2019, revealed follicular necrosis in the submucosal mucosa-associated lymphoid tissue and herniation of crypts as factors that contribute to the development of button ulcers during CSFV infection. These findings indicate that CSFV induces follicular necrosis and is one of the causative agents of button ulcers in pigs.

摘要

我们评估了经典猪瘟病毒（CSFV）在胃肠道黏膜纽扣状溃疡形成中的作用。对2019年在日本分离的CSFV亚基因型2.1毒株进行实验性感染的猪进行组织病理学和免疫组织化学分析，结果显示黏膜下黏膜相关淋巴组织中的滤泡坏死以及隐窝疝出是CSFV感染期间促成纽扣状溃疡发展的因素。这些发现表明，CSFV可诱导滤泡坏死，是猪纽扣状溃疡的致病因素之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/179d/8267204/c5ddc7023aff/jvms-83-990-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/179d/8267204/9518d187fc24/jvms-83-990-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/179d/8267204/01d7dd894f81/jvms-83-990-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/179d/8267204/c5ddc7023aff/jvms-83-990-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/179d/8267204/9518d187fc24/jvms-83-990-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/179d/8267204/01d7dd894f81/jvms-83-990-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/179d/8267204/c5ddc7023aff/jvms-83-990-g003.jpg

相似文献

1
The formation process of button ulcers in pigs experimentally infected with a subgenotype 2.1 isolate of classical swine fever virus.用经典猪瘟病毒2.1亚基因型分离株实验性感染猪后纽扣状溃疡的形成过程。
J Vet Med Sci. 2021 Jul 10;83(6):990-993. doi: 10.1292/jvms.20-0654. Epub 2021 Apr 19.
2
Efficacy evaluation of the C-strain-based vaccines against the subgenotype 2.1d classical swine fever virus emerging in China.基于C株的疫苗对中国出现的2.1d亚基因型经典猪瘟病毒的效力评估。
Vet Microbiol. 2017 Mar;201:154-161. doi: 10.1016/j.vetmic.2017.01.012. Epub 2017 Jan 17.
3
Isolation and Characterization of a Moderately Virulent Classical Swine Fever Virus Emerging in China.一株中国出现的中等毒力经典猪瘟病毒的分离与鉴定
Transbound Emerg Dis. 2017 Dec;64(6):1848-1857. doi: 10.1111/tbed.12581. Epub 2016 Sep 23.
4
Pigs immunized with a novel E2 subunit vaccine are protected from subgenotype heterologous classical swine fever virus challenge.用新型E2亚单位疫苗免疫的猪可免受亚基因型异源经典猪瘟病毒的攻击。
BMC Vet Res. 2016 Sep 9;12(1):197. doi: 10.1186/s12917-016-0823-4.
5
Genetic diversity of subgenotype 2.1 isolates of classical swine fever virus.经典猪瘟病毒2.1亚基因型分离株的遗传多样性
Infect Genet Evol. 2016 Jul;41:218-226. doi: 10.1016/j.meegid.2016.04.002. Epub 2016 Apr 13.
6
Classical swine fever virus induces pyroptosis in the peripheral lymphoid organs of infected pigs.古典猪瘟病毒在感染猪的外周淋巴器官中诱导细胞焦亡。
Virus Res. 2018 May 2;250:37-42. doi: 10.1016/j.virusres.2018.04.004. Epub 2018 Apr 5.
7
Classical swine fever virus isolates from Cuba form a new subgenotype 1.4.古巴古典猪瘟病毒分离株形成新的 1.4 亚群。
Vet Microbiol. 2013 Jan 25;161(3-4):334-8. doi: 10.1016/j.vetmic.2012.07.045. Epub 2012 Aug 3.
8
Emergence of 2.1. subgenotype of classical swine fever virus in pig population of India in 2011.2011年印度猪群中经典猪瘟病毒2.1. 亚基因型的出现。
Vet Q. 2014;34(4):224-8. doi: 10.1080/01652176.2014.973122. Epub 2014 Nov 3.
9
Chimeric (marker) C-strain viruses induce clinical protection against virulent classical swine fever virus (CSFV) and reduce transmission of CSFV between vaccinated pigs.嵌合（标记）C株病毒可诱导对强毒经典猪瘟病毒（CSFV）的临床保护，并减少CSFV在接种疫苗猪之间的传播。
Vaccine. 2001 Jan 8;19(11-12):1467-76. doi: 10.1016/s0264-410x(00)00347-9.
10
Complete genome sequence of a novel sub-subgenotype 2.1g isolate of classical swine fever virus from China.来自中国的一株新型经典猪瘟病毒2.1g亚亚基因型毒株的全基因组序列
Arch Virol. 2016 Sep;161(9):2613-7. doi: 10.1007/s00705-016-2932-6. Epub 2016 Jun 18.

引用本文的文献

1
Classical swine fever: Unveiling the complexity through a multifaceted approach.经典猪瘟：多方位揭示其复杂性。
Open Vet J. 2024 Oct;14(10):2497-2508. doi: 10.5455/OVJ.2024.v14.i10.1. Epub 2024 Oct 31.
2
Development of short hairpin RNA expression vectors targeting the internal ribosomal entry site of the classical swine fever virus genomic RNA.靶向经典猪瘟病毒基因组 RNA 内部核糖体进入位点的短发夹 RNA 表达载体的构建。
BMC Biotechnol. 2023 Sep 8;23(1):37. doi: 10.1186/s12896-023-00805-6.

本文引用的文献

1
Experimental infection of pigs with a classical swine fever virus isolated in Japan for the first time in 26 years.用26年来首次在日本分离出的一种经典猪瘟病毒对猪进行实验性感染。
J Vet Med Sci. 2019 Sep 3;81(9):1277-1284. doi: 10.1292/jvms.19-0133. Epub 2019 Jul 9.
2
Reemergence of Classical Swine Fever, Japan, 2018.2018 年日本再现古典猪瘟。
Emerg Infect Dis. 2019 Jun;25(6):1228-1231. doi: 10.3201/eid2506.181578. Epub 2019 Jun 17.
3
Genome Sequence of a Classical Swine Fever Virus of Subgenotype 2.1, Isolated from a Pig in Japan in 2018.
2018年从日本一头猪身上分离出的2.1亚基因型经典猪瘟病毒的基因组序列
Microbiol Resour Announc. 2019 Jan 17;8(3). doi: 10.1128/MRA.01362-18. eCollection 2019 Jan.
4
Epidemiology, diagnosis and control of classical swine fever: Recent developments and future challenges.《古典猪瘟的流行病学、诊断与控制：最新进展与未来挑战》
Transbound Emerg Dis. 2018 May;65 Suppl 1:248-261. doi: 10.1111/tbed.12676. Epub 2017 Aug 10.
5
Classical Swine Fever-An Updated Review.经典猪瘟——最新综述
Viruses. 2017 Apr 21;9(4):86. doi: 10.3390/v9040086.
6
Genetic variability and distribution of Classical swine fever virus.经典猪瘟病毒的遗传变异性与分布
Anim Health Res Rev. 2015 Jun;16(1):33-9. doi: 10.1017/S1466252315000109.
7
Toxicological and pathological review of concurrent occurrence of nitrite toxicity and Swine Fever in pigs.猪亚硝酸盐中毒与猪瘟并发的毒理学和病理学综述
Toxicol Int. 2014 May;21(2):186-90. doi: 10.4103/0971-6580.139806.
8
Apoptosis of thymocytes related to cytokine expression in experimental classical swine fever.
J Comp Pathol. 2002 Nov;127(4):239-48. doi: 10.1053/jcpa.2002.0587.
9
Genetic typing of classical swine fever virus.经典猪瘟病毒的基因分型
Vet Microbiol. 2000 Apr 13;73(2-3):137-57. doi: 10.1016/s0378-1135(00)00141-3.
10
Immunopathogenesis of classical swine fever: role of monocytic cells.经典猪瘟的免疫发病机制：单核细胞的作用。
Immunology. 1999 Jun;97(2):359-66. doi: 10.1046/j.1365-2567.1999.00775.x.