Huang Cui, Yuan Qiuyu, Zhang Ling, Wang Lei, Cui Shu, Zhang Kai, Zhou Xiaoqin
Chaohu Hospital, Anhui Medical University, Hefei, China.
School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, China.
Front Psychiatry. 2021 Mar 26;12:658205. doi: 10.3389/fpsyt.2021.658205. eCollection 2021.
Childhood trauma is related to substance use disorder; however, few studies have examined the relationship between childhood trauma and the age at which the drug was first used. The aim of this study was to investigate the relationship between childhood trauma and the age of first-time drug use among methamphetamine-dependent patients. Moreover, we analyzed the characteristics of adverse family environment associated with severe childhood trauma and the risk factors for starting drugs in minors. A baseline interview was conducted with 110 participants who were in detoxification, including demographic information, past substance use, and age of first-time drug use. The participants' childhood trauma experience before 18 years of age was evaluated using the simplified version of the Childhood Trauma Questionnaire (CTQ-SF). The Chinese version of the Family Environment Scale (FES-CV) was used to assess the family environment of methamphetamine-dependent patients. Among 110 non-injecting methamphetamine-dependent patients, nearly half ( = 48, 43.6%) had moderate and severe childhood trauma. Correlation analysis showed that the age of first-time drug use negatively correlated with emotional abuse ( = -0.32, < 0.01) and physical abuse ( = -0.27, < 0.01). The age of first-time drug use negatively correlated with conflict ( = -0.20, < 0.05) and independence ( = -0.22, < 0.05) of family environment, but positively correlated with intellectual-cultural orientation ( = 0.28, < 0.01). Additionally, childhood trauma factors significantly correlated with many indexes of family environment, especially cohesion ( = -0.45, < 0.01), conflict ( = 0.49, < 0.01), and independence ( = 0.33, < 0.01). Additionally, the regression model showed that when emotional abuse increased by one point, the age of first-time drug use was 0.69 years earlier. These findings suggest that a detrimental family environment can aggravate childhood trauma, and the experience of childhood emotional or physical abuse may be an effective predictor of early drug use among methamphetamine-dependent patients.
童年创伤与物质使用障碍有关；然而，很少有研究探讨童年创伤与首次使用毒品的年龄之间的关系。本研究的目的是调查甲基苯丙胺依赖患者童年创伤与首次吸毒年龄之间的关系。此外，我们分析了与严重童年创伤相关的不良家庭环境特征以及未成年人开始吸毒的危险因素。对110名正在戒毒的参与者进行了基线访谈，内容包括人口统计学信息、过去的物质使用情况以及首次吸毒年龄。使用童年创伤问卷简版（CTQ-SF）评估参与者18岁之前的童年创伤经历。采用家庭环境量表中文版（FES-CV）评估甲基苯丙胺依赖患者的家庭环境。在110名非注射甲基苯丙胺依赖患者中，近一半（n = 48，43.6%）有中度和重度童年创伤。相关分析表明，首次吸毒年龄与情感虐待（r = -0.32，P < 0.01）和身体虐待（r = -0.27，P < 0.01）呈负相关。首次吸毒年龄与家庭环境的冲突（r = -0.20，P < 0.05）和独立性（r = -0.22，P < 0.05）呈负相关，但与智力文化取向呈正相关（r = 0.28，P < 0.01）。此外，童年创伤因素与家庭环境的许多指标显著相关，尤其是亲密度（r = -0.45，P < 0.01）、冲突（r = 0.49，P < 0.01）和独立性（r = 0.33，P < 0.01）。此外，回归模型显示，当情感虐待增加1分时，首次吸毒年龄提前0.69岁。这些发现表明，有害的家庭环境会加重童年创伤，童年情感或身体虐待经历可能是甲基苯丙胺依赖患者早期吸毒的有效预测指标。
