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运动神经元病中神经元突起的肿胀

Swelling of neuronal processes in motor neuron disease.

作者信息

Sasaki S, Kamei H, Yamane K, Maruyama S

机构信息

Department of Neurology, Tokyo Women's Medical College, Japan.

出版信息

Neurology. 1988 Jul;38(7):1114-8. doi: 10.1212/wnl.38.7.1114.

DOI:10.1212/wnl.38.7.1114
PMID:3386832
Abstract

We investigated serial sections of the anterior horns of the lower lumbar cord by a modified Bielschowsky's silver impregnation, in a case of sporadic lower motor neuron disease. We paid special attention to any direct connection between the swellings of neuronal processes and the perikarya. Focal swellings of neuronal processes were occasionally directly connected with the perikarya; some had morphologic peculiarities of axons, and others originated in dendrites.

摘要

在一例散发性下运动神经元疾病患者中,我们采用改良的 Bielschowsky 银浸染法研究了下腰段脊髓前角的连续切片。我们特别关注神经元突起肿胀与胞体之间的任何直接连接。神经元突起的局灶性肿胀偶尔与胞体直接相连;一些具有轴突的形态学特征,另一些则起源于树突。

相似文献

1
Swelling of neuronal processes in motor neuron disease.运动神经元病中神经元突起的肿胀
Neurology. 1988 Jul;38(7):1114-8. doi: 10.1212/wnl.38.7.1114.
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Increase in diameter of the axonal initial segment is an early change in amyotrophic lateral sclerosis.
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Sporadic lower motor neuron disease with Lewy body-like inclusions: a new subgroup?伴有路易小体样包涵体的散发性下运动神经元病:一个新的亚组?
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Selective and asymmetric vulnerability of corticospinal and spinocerebellar tracts in motor neuron disease.运动神经元病中皮质脊髓束和脊髓小脑束的选择性及不对称性易损性
J Neurol Neurosurg Psychiatry. 1988 Jun;51(6):785-9. doi: 10.1136/jnnp.51.6.785.
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引用本文的文献

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Purkinje Cell Dendritic Swellings: A Postmortem Study of Essential Tremor and Other Cerebellar Degenerative Disorders.浦肯野细胞树突肿胀:特发性震颤和其他小脑退行性疾病的死后研究。
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2
Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons.增加神经丝亚基NF-M的表达会降低轴突NF-H,抑制径向生长,并导致运动神经元中神经丝的积累。
J Cell Biol. 1995 Sep;130(6):1413-22. doi: 10.1083/jcb.130.6.1413.
3
Synaptic loss in the proximal axon of anterior horn neurons in motor neuron disease.
Acta Neuropathol. 1995;90(2):170-5. doi: 10.1007/BF00294317.
4
Phosphorylated high molecular weight neurofilament protein in lower motor neurons in amyotrophic lateral sclerosis and other neurodegenerative diseases involving ventral horn cells.
Acta Neuropathol. 1990;79(4):402-8. doi: 10.1007/BF00308716.
5
Widely distributed Bunina bodies and spheroids in a case of atypical sporadic amyotrophic lateral sclerosis.一例非典型散发性肌萎缩侧索硬化症患者中广泛分布的布尼纳小体和球状体。
Acta Neuropathol. 1991;81(3):349-53. doi: 10.1007/BF00305880.
6
Clarke's column in sporadic amyotrophic lateral sclerosis.
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