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一项在印度北阿坎德邦开展的为期13年的基于医院的尿路结石病发病趋势研究。

A 13 year hospital based study on the Trend of Urinary Stone Disease in Uttarakhand, India.

作者信息

Kakkar Monica, Kakkar Rakesh

机构信息

Department of Biochemistry, NRI Medical College, Guntur, Andhra Pradesh, India.

Department of Community and Family Medicine, All India Institute of Medical Sciences, Mangalagiri, Guntur, Andhra Pradesh, India.

出版信息

Nepal J Epidemiol. 2021 Mar 31;11(1):949-958. doi: 10.3126/nje.v11i1.35896. eCollection 2021 Mar.

Abstract

BACKGROUND

The present retrospective study on urinary stone disease in the Uttarakhand state was necessitated as no study has been done yet.

METHODS

A 13 year retrospective study (from 2005 to 2018) was conducted on the urinary stones removed from the patients, admitted at Himalayan Institute of Medical Sciences, Dehradun. The incidence of the disease, site of stones in urinary tract upon diagnosis, composition of removed stones and occurrence of a possible co-relationship between the incidence of the urinary stone disease at different times, age, sex, religion of the patients was investigated.

RESULTS

The frequency of occurrence of urinary stones in males was found to be almost three times more as compared to their female counterparts. The above trend was consistent over the entire period of the study. Interestingly, in the Muslim and Sikh population of the area, females were found to be less prone to the problem as compared to their Hindu counterparts. However, in all religious groups, 21-40 years old subjects were found to be most susceptible to the problem and approximately 90% of the urinary stones were recovered from the kidneys and primarily composed of calcium oxalate.

CONCLUSION

The co-relationship between the occurrence of urinary stones with age, sex of the patients, their religion & site of stones on diagnosis was found to be statistically significant.

摘要

背景

由于此前尚未开展过相关研究,因此有必要对北阿坎德邦的尿路结石病进行本次回顾性研究。

方法

对在德拉敦喜马拉雅医学科学研究所住院治疗的患者所排出的尿路结石进行了一项为期13年(2005年至2018年)的回顾性研究。调查了该疾病的发病率、诊断时尿路结石的位置、排出结石的成分,以及尿路结石病发病率在不同时间、患者年龄、性别、宗教之间可能存在的相互关系。

结果

发现男性尿路结石的发生率几乎是女性的三倍。在整个研究期间,上述趋势保持一致。有趣的是,在该地区的穆斯林和锡克教人群中,与印度教女性相比,发现女性患该疾病的可能性较小。然而,在所有宗教群体中,21至40岁的人群被发现最易患该疾病,并且约90%的尿路结石是从肾脏中取出的,主要成分为草酸钙。

结论

发现尿路结石的发生与患者年龄、性别、宗教以及诊断时结石位置之间的相互关系具有统计学意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ffb/8033642/47d4f648dd31/nje-11-949-g001.jpg

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