Jakobsen Rasmus Kirial, Bonde Alexander, Sillesen Martin
Department of Surgical Gastroenterology and Transplantation C-TX, Rigshospitalet, Kobenhavn, Denmark.
Center for Surgical Translational and Artificial Intelligence Research (CSTAR), Copenhagen, Denmark.
Trauma Surg Acute Care Open. 2021 Mar 26;6(1):e000667. doi: 10.1136/tsaco-2020-000667. eCollection 2021.
Trauma is associated with a significant risk of post-trauma complications (PTCs). These include thromboembolic events, strokes, infections, and failure of organ systems (eg, kidney failure). Although care of the trauma patient has evolved during the last decade, whether this has resulted in a reduction in specific PTCs is unknown. We hypothesize that the incidence of PTCs has been decreasing during a 10-year period from 2007 to 2017.
This is a descriptive study of trauma patients originating from level 1, 2, 3, and 4 trauma centers in the USA, obtained via the Trauma Quality Improvement Program (TQIP) database from 2007 to 2017. PTCs documented throughout the time frame were extracted along with demographic variables. Multiple regression modeling was used to associate admission year with PTCs, while controlling for age, gender, Glasgow Coma Scale score, and Injury Severity Score.
Data from 8 720 026 trauma patients were extracted from the TQIP database. A total of 366 768 patients experienced one or more PTCs. There was a general decrease in the incidence of PTCs during the study period, with the overall incidence dropping from 7.0% in 2007 to 2.8% in 2017. Multiple regression identified a slight decrease in incidence in all PTCs, although deep surgical site infection (SSI), deep venous thrombosis (DVT), and stroke incidences increased when controlled for confounders.
Overall the incidence of PTCs dropped during the 10-year study period, although deep SSI, DVT, stroke, and cardiac arrest increased during the study period. Better risk prediction tools, enabling a precision medicine approach, are warranted to identify at-risk patients.
III.
创伤与创伤后并发症(PTCs)的重大风险相关。这些并发症包括血栓栓塞事件、中风、感染以及器官系统功能衰竭(如肾衰竭)。尽管在过去十年中创伤患者的护理有所发展,但这是否导致特定PTCs的减少尚不清楚。我们假设在2007年至2017年的10年期间,PTCs的发生率一直在下降。
这是一项对来自美国1、2、3和4级创伤中心的创伤患者的描述性研究,数据通过创伤质量改进计划(TQIP)数据库于2007年至2017年获取。在整个时间段内记录的PTCs以及人口统计学变量被提取出来。使用多元回归模型将入院年份与PTCs相关联,同时控制年龄、性别、格拉斯哥昏迷量表评分和损伤严重程度评分。
从TQIP数据库中提取了8720026名创伤患者的数据。共有366768名患者经历了一种或多种PTCs。在研究期间,PTCs的发生率总体呈下降趋势,总体发生率从2007年的7.0%降至2017年的2.8%。多元回归分析发现所有PTCs的发生率略有下降,尽管在控制混杂因素后,深部手术部位感染(SSI)、深静脉血栓形成(DVT)和中风的发生率有所增加。
总体而言,在10年的研究期间,PTCs的发生率下降了,尽管在研究期间深部SSI、DVT、中风和心脏骤停的发生率有所增加。需要更好的风险预测工具,以实现精准医疗方法,来识别高危患者。
III级。