• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

经玻璃体腔注射阿柏西普成功治疗2型脉络膜新生血管后,局灶性脉络膜凹陷消失。

Focal choroidal excavation disappearing after successful treatment of type 2 choroidal neovascularization with intravitreal aflibercept.

作者信息

Sato Tatsuhiko, Yasukawa Tsutomu, Hayashi Ken

机构信息

Hayashi Eye Hospital, 4-23-35 Hakataekimae Hakata-ku, Fukuoka, 812-0011, Japan.

Department of Ophthalmology & Visual Science, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi Mizuho-cho Mizuho-ku, Nagoya, 467-8601, Japan.

出版信息

Am J Ophthalmol Case Rep. 2021 Mar 27;22:101078. doi: 10.1016/j.ajoc.2021.101078. eCollection 2021 Jun.

DOI:10.1016/j.ajoc.2021.101078
PMID:33869893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8044643/
Abstract

PURPOSE

To report a case with focal choroidal excavation (FCE) accompanied by type 2 choroidal neovascularization (CNV), in which the CNV was successfully treated with intravitreal aflibercept, after which the FCE was no longer detectable.

OBSERVATIONS

A conforming type of FCE was detected in the left eye of a 34-year-old Japanese man who visited our hospital for a second opinion regarding treatment for his right eye. Three months later, type 2 CNV developed in the region corresponding to the FCE in the left eye. After treatment with intravitreal aflibercept, the CNV disappeared, and FCE was no longer detected. No recurrence has been observed in the 12 months following the treatment.

CONCLUSIONS AND IMPORTANCE

Although the etiology of FCE has not been fully elucidated, we discussed the mechanisms underlying its occurrence, its association with CNV, and the disappearance of both conditions after treatment.

摘要

目的

报告一例伴有2型脉络膜新生血管(CNV)的局限性脉络膜凹陷(FCE)病例,该病例经玻璃体内注射阿柏西普成功治疗CNV后,FCE不再可检测到。

观察结果

一名34岁日本男性因右眼治疗问题前来我院寻求二次诊疗意见,其左眼检测到符合类型的FCE。三个月后,左眼FCE对应区域出现2型CNV。经玻璃体内注射阿柏西普治疗后,CNV消失,FCE不再可检测到。治疗后的12个月内未观察到复发。

结论与意义

尽管FCE的病因尚未完全阐明,但我们讨论了其发生的潜在机制、与CNV的关联以及治疗后两种情况均消失的现象。

相似文献

1
Focal choroidal excavation disappearing after successful treatment of type 2 choroidal neovascularization with intravitreal aflibercept.经玻璃体腔注射阿柏西普成功治疗2型脉络膜新生血管后,局灶性脉络膜凹陷消失。
Am J Ophthalmol Case Rep. 2021 Mar 27;22:101078. doi: 10.1016/j.ajoc.2021.101078. eCollection 2021 Jun.
2
Focal choroidal excavation complicated by choroidal neovascularization.局限性脉络膜凹陷合并脉络膜新生血管。
Ophthalmology. 2014 Jan;121(1):246-250. doi: 10.1016/j.ophtha.2013.08.014. Epub 2013 Oct 4.
3
Case Report: Complete tomographic resolution of focal choroidal excavation complicated with choroidal neovascularization after anti-VEGF treatment.病例报告:抗 VEGF 治疗后伴脉络膜新生血管的局灶性脉络膜凹陷完全层析分辨率消退。
F1000Res. 2023 Oct 5;12:1270. doi: 10.12688/f1000research.141099.1. eCollection 2023.
4
Choroidal neovascularization emerged right from the focal choroidal excavation in eyes with central serous chorioretinopathy post half-dose photodynamic therapy: a case report.中心性浆液性脉络膜视网膜病变半剂量光动力治疗后,脉络膜新生血管从病灶性脉络膜凹陷处直接出现:一例报告
BMC Ophthalmol. 2019 Mar 8;19(1):68. doi: 10.1186/s12886-019-1081-6.
5
A rare case of focal choroidal excavation associated choroidal neovascularization in angioid streaks.一例罕见的与血管样条纹相关的局灶性脉络膜凹陷合并脉络膜新生血管病例。
Oman J Ophthalmol. 2019 Oct 11;12(3):200-202. doi: 10.4103/ojo.OJO_61_2018. eCollection 2019 Sep-Dec.
6
Focal choroidal excavation complicated with choroidal neovascularization in young and middle aged patients.中青年患者的局限性脉络膜凹陷合并脉络膜新生血管形成
Int J Ophthalmol. 2019 Jun 18;12(6):980-984. doi: 10.18240/ijo.2019.06.16. eCollection 2019.
7
Clinical and spectral-domain optical coherence tomography findings in patients with focal choroidal excavation.局限性脉络膜凹陷患者的临床和谱域光学相干断层扫描表现。
Ophthalmology. 2014 May;121(5):1029-35. doi: 10.1016/j.ophtha.2013.11.043. Epub 2014 Jan 16.
8
Development of Secondary Choroidal Neovascularization in Focal Choroidal Excavation of Punctate Inner Choroidopathy.特发性脉络膜凹部局限性脉络膜病变的继发脉络膜新生血管的发展。
Ocul Immunol Inflamm. 2020;28(1):20-25. doi: 10.1080/09273948.2018.1540708. Epub 2018 Nov 13.
9
Focal Choroidal Excavation and Central Serous Chorioretinopathy Following Choroidal Neovascularization: A Longitudinal Case Study.脉络膜新生血管形成后出现的局限性脉络膜凹陷与中心性浆液性脉络膜视网膜病变:一项纵向病例研究。
J Vitreoretin Dis. 2019 Dec 11;4(2):157-162. doi: 10.1177/2474126419888135. eCollection 2020 Mar-Apr.
10
Focal Choroidal Excavation in a Case of Choroidal Osteoma Associated with Choroidal Neovascularization.脉络膜骨瘤合并脉络膜新生血管病例中的局限性脉络膜凹陷
J Ophthalmic Vis Res. 2020 Aug 6;15(3):419-423. doi: 10.18502/jovr.v15i3.7461. eCollection 2020 Jul-Sep.

本文引用的文献

1
Pachychoroid disease.脉络膜增厚性疾病。
Eye (Lond). 2019 Jan;33(1):14-33. doi: 10.1038/s41433-018-0158-4. Epub 2018 Jul 11.
2
The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD.氧化应激和炎症对非新生血管性年龄相关性黄斑变性中视网膜色素上皮细胞变性的影响。
Prog Retin Eye Res. 2017 Sep;60:201-218. doi: 10.1016/j.preteyeres.2017.03.002. Epub 2017 Mar 20.
3
FOCAL CHOROIDAL EXCAVATION AND ITS ASSOCIATION WITH PACHYCHOROID SPECTRUM DISORDERS: A Review of the Literature and Multimodal Imaging Findings.
局灶性脉络膜凹陷及其与厚脉络膜谱系疾病的关联:文献综述与多模态影像学研究结果
Retina. 2017 Feb;37(2):199-221. doi: 10.1097/IAE.0000000000001345.
4
Multimodal Imaging Evaluations of Focal Choroidal Excavations in Eyes with Central Serous Chorioretinopathy.中心性浆液性脉络膜视网膜病变患者眼部局灶性脉络膜凹陷的多模态成像评估
J Ophthalmol. 2016;2016:7073083. doi: 10.1155/2016/7073083. Epub 2016 Jun 29.
5
Prevalence and clinical correlates of focal choroidal excavation in eyes with age-related macular degeneration, polypoidal choroidal vasculopathy and central serous chorioretinopathy.年龄相关性黄斑变性、息肉样脉络膜血管病变和中心性浆液性脉络膜视网膜病变患者中局限性脉络膜凹陷的患病率及临床相关性
Br J Ophthalmol. 2016 Jul;100(7):918-923. doi: 10.1136/bjophthalmol-2015-307055. Epub 2015 Oct 26.
6
The absence of focal choroidal excavation in children and adolescents without retinal or choroidal disorders or ocular trauma.在没有视网膜或脉络膜疾病或眼外伤的儿童和青少年中不存在局灶性脉络膜凹陷。
Eye (Lond). 2015 Jun;29(6):841-2. doi: 10.1038/eye.2015.6. Epub 2015 Feb 13.
7
Association of focal choroidal excavation with age-related macular degeneration.局限性脉络膜凹陷与年龄相关性黄斑变性的关联
Invest Ophthalmol Vis Sci. 2014 Sep 4;55(9):6046-54. doi: 10.1167/iovs.14-14723.
8
Evaluation of focal choroidal excavation in the macula using swept-source optical coherence tomography.应用扫频源光学相干断层扫描评估黄斑区局灶性脉络膜凹陷。
Eye (Lond). 2014 Sep;28(9):1088-94. doi: 10.1038/eye.2014.78. Epub 2014 Jun 20.
9
Morphologic features of focal choroidal excavation on spectral domain optical coherence tomography with simultaneous angiography.频域光学相干断层扫描联合血管造影术观察局限性脉络膜凹陷的形态学特征
Retina. 2014 Jul;34(7):1407-14. doi: 10.1097/IAE.0000000000000108.
10
Clinical and spectral-domain optical coherence tomography findings in patients with focal choroidal excavation.局限性脉络膜凹陷患者的临床和谱域光学相干断层扫描表现。
Ophthalmology. 2014 May;121(5):1029-35. doi: 10.1016/j.ophtha.2013.11.043. Epub 2014 Jan 16.