经玻璃体腔注射阿柏西普成功治疗2型脉络膜新生血管后，局灶性脉络膜凹陷消失。
Focal choroidal excavation disappearing after successful treatment of type 2 choroidal neovascularization with intravitreal aflibercept.
作者信息
Sato Tatsuhiko, Yasukawa Tsutomu, Hayashi Ken
机构信息
Hayashi Eye Hospital, 4-23-35 Hakataekimae Hakata-ku, Fukuoka, 812-0011, Japan.
Department of Ophthalmology & Visual Science, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi Mizuho-cho Mizuho-ku, Nagoya, 467-8601, Japan.
出版信息
Am J Ophthalmol Case Rep. 2021 Mar 27;22:101078. doi: 10.1016/j.ajoc.2021.101078. eCollection 2021 Jun.
PURPOSE
To report a case with focal choroidal excavation (FCE) accompanied by type 2 choroidal neovascularization (CNV), in which the CNV was successfully treated with intravitreal aflibercept, after which the FCE was no longer detectable.
OBSERVATIONS
A conforming type of FCE was detected in the left eye of a 34-year-old Japanese man who visited our hospital for a second opinion regarding treatment for his right eye. Three months later, type 2 CNV developed in the region corresponding to the FCE in the left eye. After treatment with intravitreal aflibercept, the CNV disappeared, and FCE was no longer detected. No recurrence has been observed in the 12 months following the treatment.
CONCLUSIONS AND IMPORTANCE
Although the etiology of FCE has not been fully elucidated, we discussed the mechanisms underlying its occurrence, its association with CNV, and the disappearance of both conditions after treatment.
目的
报告一例伴有2型脉络膜新生血管（CNV）的局限性脉络膜凹陷（FCE）病例，该病例经玻璃体内注射阿柏西普成功治疗CNV后，FCE不再可检测到。
观察结果
一名34岁日本男性因右眼治疗问题前来我院寻求二次诊疗意见，其左眼检测到符合类型的FCE。三个月后，左眼FCE对应区域出现2型CNV。经玻璃体内注射阿柏西普治疗后，CNV消失，FCE不再可检测到。治疗后的12个月内未观察到复发。
结论与意义
尽管FCE的病因尚未完全阐明，但我们讨论了其发生的潜在机制、与CNV的关联以及治疗后两种情况均消失的现象。
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