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Metabolic biomarkers in community obese children: effect of obstructive sleep apnea and its treatment.社区肥胖儿童的代谢生物标志物:阻塞性睡眠呼吸暂停及其治疗的影响
Sleep Med. 2017 Sep;37:1-9. doi: 10.1016/j.sleep.2017.06.002. Epub 2017 Jun 22.
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Obstructive Sleep Apnea and Pulmonary Hypertension in Children.儿童阻塞性睡眠呼吸暂停与肺动脉高压。
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Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline.成人阻塞性睡眠呼吸暂停诊断检测临床实践指南:美国睡眠医学学会临床实践指南
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7
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8
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睡眠临床记录应用于巴西儿童及其与意大利儿童的比较。

Sleep Clinical Record application in Brazilian children and its comparison with Italian children.

作者信息

Corrêa Camila de Castro, Weber Silke Anna Theresa, Evangelisti Melania, Villa Maria Pia

机构信息

Department of Ophtalmology, Otolaryngology and Head and Neck Surgery, Botucatu Medical School, State University Sao Paulo, UNESP, Botucatu, Sao Paulo, Brazil.

Pediatric Sleep Disease Center, Child Neurology, NESMOS Department, School of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.

出版信息

Sleep Med X. 2019 Aug 8;1:100008. doi: 10.1016/j.sleepx.2019.100008. eCollection 2019 Dec.

DOI:10.1016/j.sleepx.2019.100008
PMID:33870167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8041129/
Abstract

OBJECTIVE

To apply the Sleep Clinical Record (SCR) to a sample of Brazilian children with sleep complaints, to compare the results with Italian children, and to identify variables that influence phenotype.

METHODS

Brazilian and Italian children, 4-11 years of age and matched for age, gender, obesity, and apnea-hypopnea index and who presented with complaints related to sleep, were selected. The instrument used was the SCR, and the procedure used was full-night cardiorespiratory monitoring.

RESULTS

The sample consisted of 51 Brazilian children and 102 Italian children. Brazilian children presented with oral breathing (55%), tonsillar hypertrophy (69%), Friedman palate position (88%), malocclusion (84%), and OSAS score (Brouilette questionnaire) (55%). The SCR among obese Brazilian children was higher as compared to that in nonobese subjects (obese, 10.84 vs nonobese, 9.13;  = 0.03). In the comparison between Brazilian and Italian children, the total Brazilian SCR was higher than the Italian SCR score (Brazilian SCR, 10.21 ± 7.56; Italian SCR, 8.95 ± 2.55;  = 0.002). The Italian SCR score was influenced by obesity, whereas the Brazilian SCR was influenced by others symptoms (daytime sleepiness, enuresis, nocturnal choking, headache, limb movements).

CONCLUSION

Brazilian children with sleep-disordered breathing show a higher SCR score as compared to Italian children. Obesity and tonsillar hypertrophy, Friedman palate position alteration, and dental malocclusion further influenced the total SCR score among Brazilian children. This may be due to access difficulties in Brazil where children should have more assistance to obtain medical care.

摘要

目的

将睡眠临床记录(SCR)应用于有睡眠问题的巴西儿童样本,与意大利儿童的结果进行比较,并确定影响表型的变量。

方法

选取4至11岁、年龄、性别、肥胖程度和呼吸暂停低通气指数相匹配且有睡眠相关问题的巴西和意大利儿童。使用的工具是SCR,采用的程序是全夜心肺监测。

结果

样本包括51名巴西儿童和102名意大利儿童。巴西儿童存在口呼吸(55%)、扁桃体肥大(69%)、弗里德曼腭位(88%)、错牙合(84%)以及OSAS评分(布鲁耶特问卷)(55%)。肥胖巴西儿童的SCR高于非肥胖儿童(肥胖儿童为10.84,非肥胖儿童为9.13;P = 0.03)。在巴西和意大利儿童的比较中,巴西SCR总分高于意大利SCR评分(巴西SCR为10.21±7.56;意大利SCR为8.95±2.55;P = 0.002)。意大利SCR评分受肥胖影响,而巴西SCR受其他症状(日间嗜睡、遗尿、夜间窒息、头痛、肢体运动)影响。

结论

与意大利儿童相比,有睡眠呼吸障碍的巴西儿童SCR评分更高。肥胖、扁桃体肥大、弗里德曼腭位改变和牙列不齐进一步影响了巴西儿童的SCR总分。这可能是由于巴西存在就医困难,儿童应获得更多医疗救助。