de Moura Alonso Juliana, de Melo-Neto Gabriel Barbosa, Dos Santos Bruna, Mogollón García Henry David, Paim Kamila Pinheiro, Pinheiro Ferreira João Carlos, Santos Schmidt Elizabeth Moreira, da Silva Amanda Nogueira Ferreira, da Cunha Grazielly Marques, Takahira Regina Kiomi, Ferreira Canuto Lucas Emanuel, Papa Frederico Ozanam, Hussni Carlos Alberto
Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Vet Rec. 2021 Oct;189(7):e240. doi: 10.1002/vetr.240. Epub 2021 Apr 18.
This study aimed to evaluate the inflammatory response of miniature horses subjected to open and half-closed orchiectomy by physical examination, blood cell count, peritoneal fluid evaluation, total plasma protein, fibrinogen, and serum amyloid A (SAA) concentrations.
Thirteen male healthy miniature horses were divided into two groups, according to the surgical approach: half-closed technique (HCT) and open technique (OT). The HCT group was subjected to ligation of the spermatic cord followed by its sharp incision, and closure of the vaginal tunic, and the OT group was only submitted to cord ligation. Prior to, and at 1, 2, 3 and 5 days after the surgery, a general and specific physical examination, blood cell counts, total plasma protein, peritoneal fluid evaluation, fibrinogen, and SAA concentrations were performed.
Higher postoperative perilesional oedema, rectal temperature, and fibrinogen were observed in the HCT group. Groups did not differ as to SAA concentrations. The evaluated local and systemic inflammatory profile demonstrated that, as expected, surgery resulted in inflammation in both groups.
The group subjected to the HCT showed a more intense and lasting inflammatory response. However, despite the different postoperative inflammatory profiles, both groups presented a favourable outcome and recovery.
本研究旨在通过体格检查、血细胞计数、腹腔液评估、总血浆蛋白、纤维蛋白原和血清淀粉样蛋白A（SAA）浓度，评估接受开放式和半封闭式睾丸切除术的小型马的炎症反应。
根据手术方式，将13匹健康雄性小型马分为两组：半封闭式技术（HCT）组和开放式技术（OT）组。HCT组先结扎精索，然后锐性切开精索，并闭合鞘膜，OT组仅进行精索结扎。在手术前以及术后第1、2、3和5天，进行全面和特定的体格检查、血细胞计数、总血浆蛋白、腹腔液评估、纤维蛋白原和SAA浓度检测。
HCT组术后病灶周围水肿、直肠温度和纤维蛋白原水平较高。两组的SAA浓度无差异。评估的局部和全身炎症特征表明，正如预期的那样，手术导致两组均出现炎症。
接受HCT的组表现出更强烈和持久的炎症反应。然而，尽管术后炎症特征不同，但两组均取得了良好的结果和恢复情况。
