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家兔生长、胴体和肉质性状标记辅助选择的候选基因

Candidate genes for marker-assisted selection for growth, carcass and meat quality traits in rabbits.

作者信息

Helal Mostafa, Hany Nora, Maged Marya, Abdelaziz Mariam, Osama Nourhan, Younan Youstina W, Ismail Youssef, Abdelrahman Ramah, Ragab Mohamed

机构信息

Department of Animal Production, Faculty of Agriculture, Cairo University, Giza, Egypt.

Biotechnolgy Program, Faculty of Agriculture, Cairo University, Giza, Egypt.

出版信息

Anim Biotechnol. 2022 Dec;33(7):1691-1710. doi: 10.1080/10495398.2021.1908315. Epub 2021 Apr 19.

DOI:10.1080/10495398.2021.1908315
PMID:33872113
Abstract

Growth and meat production are the most relevant targets for animal breeders, there are strong relationships between animal growth regulation, body composition and meat quality. Therefore, it is essential to identify the genetic factors that are controlling growth, carcass, and meat quality traits and to explore the correlations between identified genes of those traits. Identification of candidate genes may shift rabbit breeding from classical to modern approaches, which offer great potential to accelerate genetic improvement plans, especially in developing countries. The current work reviews several genes and mutations affecting growth, carcass and meat quality traits. These candidate genes and mutations can be incorporated into MAS programs to improve rabbit breeds especially local breeds, provided that a reasonable proportion of trait additive genetic variance is explained by the significant marker. Furthermore, we highlighted the indispensable need for more researches investigating candidate genes for different traits.

摘要

生长和肉品生产是动物育种者最关注的目标,动物生长调节、身体组成和肉质之间存在紧密联系。因此,识别控制生长、胴体和肉质性状的遗传因素,并探索这些性状的已识别基因之间的相关性至关重要。候选基因的识别可能会使兔子育种从传统方法转向现代方法,这为加速遗传改良计划提供了巨大潜力,尤其是在发展中国家。当前的工作综述了几个影响生长、胴体和肉质性状的基因及突变。这些候选基因和突变可以纳入标记辅助选择(MAS)计划,以改良兔子品种,特别是地方品种,前提是显著标记能解释合理比例的性状加性遗传方差。此外,我们强调了开展更多研究以探究不同性状候选基因的迫切需求。

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