Faculty of Health Sciences, The Joyce & Irving Goldman Medical School, Ben-Gurion University of the Negev, Beer Sheva, Israel.
The Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Int J Gynaecol Obstet. 2021 Aug;154(2):297-303. doi: 10.1002/ijgo.13715. Epub 2021 May 12.
To evaluate the effect of the coronavirus disease 2019 (COVID-19) mask-wearing on hematological laboratory components and obstetrical outcomes among women delivering during the COVID-19 pandemic.
Laboratory results and obstetrical outcomes of women with singleton gestations, admitted for delivery during the COVID-19 mask-wearing period (April-June 2020) were compared with those of women delivering during the parallel period in 2019 and with a larger cohort derived from nine pre-pandemic years (March 2011-April 2020).
Overall, 1838 women delivered during the COVID-19 pandemic. Compared with the pre-pandemic period, mean hemoglobin and fibrinogen levels were significantly higher during the mask-wearing period (12.15 ± 1.1 vs 11.96 ± 1.2, P < 0.001 and 472 ± 103.6 vs 448 ± 85.1 mg/dl, P < 0.001, respectively). Platelet levels were lower (200 ± 56.0 vs 206 ± 57.5 K/µl, P < 0.001). The rate of delivery at <34 weeks of gestation was lower during the mask-wearing period (1.1% vs 2%, odds ratio [OR] 0.57, 95% confidence intervals [CI] 0.37-0.88, P = 0.01), whereas cesarean delivery and postpartum hemorrhage rates were higher (26.7% vs 24.4%, OR 1.13, 95% CI 1.02-1.25, P = 0.022 and 4.1% vs 2.8%, OR 1.5, 95% CI 1.2-1.8, P = 0.001, respectively).
A hard-to-ventilate space created by wearing a mask during the COVID-19 era may be the underlying cause of the observed higher hemoglobin level among pregnant women, possibly affecting obstetrical outcomes.
评估 2019 年冠状病毒病（COVID-19）戴口罩对 COVID-19 大流行期间分娩妇女的血液学实验室指标和产科结局的影响。
比较 COVID-19 戴口罩期间（2020 年 4 月至 6 月）单胎妊娠妇女的实验室结果和产科结局，与 2019 年同期以及来自 9 个大流行前年份（2011 年 3 月至 2020 年 4 月）的较大队列的结果进行比较。
总体而言，有 1838 名妇女在 COVID-19 大流行期间分娩。与大流行前时期相比，口罩佩戴期间平均血红蛋白和纤维蛋白原水平显著升高（12.15±1.1 与 11.96±1.2，P<0.001 和 472±103.6 与 448±85.1 mg/dl，P<0.001，分别）。血小板水平较低（200±56.0 与 206±57.5 K/µl，P<0.001）。口罩佩戴期间<34 周分娩率较低（1.1%与 2%，比值比[OR]0.57，95%置信区间[CI]0.37-0.88，P=0.01），而剖宫产率和产后出血率较高（26.7%与 24.4%，OR 1.13，95% CI 1.02-1.25，P=0.022 和 4.1%与 2.8%，OR 1.5，95% CI 1.2-1.8，P=0.001，分别）。
在 COVID-19 期间佩戴口罩产生的通风不良空间可能是孕妇血红蛋白水平升高的潜在原因，可能会影响产科结局。
