Maccabi Healthcare Services, Tel Aviv, Israel.
Mayanei HaYeshua Medical Center, affiliated with the Sackler faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
J Cosmet Dermatol. 2021 Jun;20(6):1648-1654. doi: 10.1111/jocd.14152. Epub 2021 May 3.
Botulinum neurotoxin is one of the most versatile and widely used medical products in the world.
The review's focus is the plastic and dermatologic uses of botulinum neurotoxin currently supported by published data.
Relevant clinical articles regarding botulinum neurotoxin use in plastic surgery, dermatology, and general esthetic literature were searched and reviewed.
The search yielded 258 studies. Two hundred articles were excluded following title and abstract review. Twenty-one studies were excluded following full-text screening. A total of 37 studies remained and were discussed in this review.
Botulinum neurotoxin is widely used for numerous off-label indications from head to toe. Some uses are well documented, and their safety has been demonstrated in controlled trials, yet most remain poorly researched.
肉毒神经毒素是世界上用途最广泛、应用最广泛的医疗产品之一。
本综述的重点是目前已有数据支持的肉毒神经毒素在整形和皮肤科方面的应用。
检索并回顾了有关肉毒神经毒素在整形手术、皮肤科和一般美容文献中的应用的相关临床文章。
搜索结果产生了 258 项研究。在标题和摘要审查后，排除了 200 篇文章。在全文筛选后，又排除了 21 项研究。共有 37 项研究被保留并在本综述中进行了讨论。
肉毒神经毒素广泛用于从头到脚的许多未经批准的适应症。有些用途有充分的记录，其安全性已在对照试验中得到证实，但大多数仍缺乏研究。
