Aesthet Surg J. 2023 Oct 13;43(11):NP962-NP974. doi: 10.1093/asj/sjad151.
Treatment of wrinkles and dynamic lines with botulinum toxin has been a routine practice for years in aesthetic clinical settings. The effective treatment of wrinkles requires a comprehensive understanding of facial expression muscles and their interactions, the mechanism of action of botulinum toxin, and individual patient preferences. The dose adjustment practice and injection technique of physicians are affected by cultural differences; most Asian patients prefer natural-looking results. This article aims to present an expert consensus on the injection sites, doses, and levels of botulinum toxin for various indications in Asians, with the hope of providing guidance to some clinicians. This consensus paper reviews LetibotulinumtoxinA for patient evaluation, dosage, and delivery techniques in Asians from the time LetibotulinumtoxinA was approved up to December 2022. Panelists proposed individualized treatment plans for botulinum toxin type A (BTxA) treatments in 3 areas-wrinkle removal, contour adjustment, and face lifting-for Asians based on their extensive experience and knowledge of facial anatomy. When using a different BTxA, clinicians should start with a conservative dose and carefully individualize the treatment for each patient, and adjust it according to feedback to obtain a higher satisfaction level.
多年来，肉毒毒素一直是美容临床治疗皱纹和动态线的常规方法。有效治疗皱纹需要全面了解面部表情肌及其相互作用、肉毒毒素的作用机制以及患者的个人喜好。医生的剂量调整实践和注射技术受到文化差异的影响；大多数亚洲患者更喜欢自然的效果。本文旨在为亚洲人各种适应症的肉毒毒素注射部位、剂量和水平提出专家共识，希望能为一些临床医生提供指导。本共识文件回顾了自利妥昔单抗毒素 A 获得批准至 2022 年 12 月期间，亚洲患者的患者评估、剂量和给药技术。根据他们对面部解剖学的丰富经验和知识，小组成员针对亚洲人在 3 个领域（皱纹去除、轮廓调整和面部提升）的肉毒毒素 A（BTxA）治疗提出了个体化治疗方案。使用不同的 BTxA 时，临床医生应从保守剂量开始，并根据每位患者的情况仔细进行个体化治疗，并根据反馈进行调整，以获得更高的满意度。
