• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

长新冠综合征。

'Long COVID' syndrome.

机构信息

Royal Free London NHS Foundation Trust, London, UK

Royal Free London NHS Foundation Trust, London, UK.

出版信息

BMJ Case Rep. 2021 Apr 19;14(4):e241485. doi: 10.1136/bcr-2020-241485.

DOI:10.1136/bcr-2020-241485
PMID:33875508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8057566/
Abstract

SARS-CoV-2 has resulted in a global pandemic and an unprecedented public health crisis. Recent literature suggests the emergence of a novel syndrome known as 'long COVID', a term used to describe a diverse set of symptoms that persist after a minimum of 4 weeks from the onset of a diagnosed COVID-19 infection. Common symptoms include persistent breathlessness, fatigue and cough. Other symptoms reported include chest pain, palpitations, neurological and cognitive deficits, rashes, and gastrointestinal dysfunction. We present a complex case of a previously well 28-year-old woman who was diagnosed with COVID-19. After resolution of her acute symptoms, she continued to experience retrosternal discomfort, shortness of breath, poor memory and severe myalgia. Investigations yielded no significant findings. Given no alternative diagnosis, she was diagnosed with 'long COVID'.

摘要

SARS-CoV-2 引发了全球大流行和前所未有的公共卫生危机。最近的文献表明,出现了一种新的综合征,称为“长新冠”,用于描述一种从 COVID-19 感染确诊后至少 4 周持续存在的多种症状。常见症状包括持续的呼吸急促、疲劳和咳嗽。其他报告的症状包括胸痛、心悸、神经和认知缺陷、皮疹和胃肠道功能障碍。我们报告了一例先前健康的 28 岁女性的复杂病例,她被诊断患有 COVID-19。急性症状缓解后,她仍持续感到胸骨后不适、呼吸急促、记忆力差和严重的肌痛。检查未发现明显异常。由于没有其他诊断,她被诊断为“长新冠”。

相似文献

1
'Long COVID' syndrome.长新冠综合征。
BMJ Case Rep. 2021 Apr 19;14(4):e241485. doi: 10.1136/bcr-2020-241485.
2
Sex-Related Differences in Long-COVID-19 Syndrome.长新冠综合征的性别差异。
J Womens Health (Larchmt). 2022 May;31(5):620-630. doi: 10.1089/jwh.2021.0411. Epub 2022 Mar 25.
3
[Practical management of long Covid disease in outpatients: illustration by clinical cases].[门诊长期新冠疾病的实际管理:临床病例说明]
Rev Med Suisse. 2021 Nov 10;17(758):1915-1921.
4
Long COVID Clusters of Symptoms Persist beyond Two Years after Infection: Insights from the CARDIO COVID 20-21 Registry.感染后两年以上仍存在长期新冠症状群:CARDIO COVID 20-21 注册研究的启示。
Viruses. 2024 Jun 26;16(7):1028. doi: 10.3390/v16071028.
5
Symptom Profiles and Progression in Hospitalized and Nonhospitalized Patients with Coronavirus Disease, Colorado, USA, 2020.2020 年美国科罗拉多州住院和非住院的冠状病毒疾病患者的症状特征和进展情况。
Emerg Infect Dis. 2021 Feb;27(2):385-395. doi: 10.3201/eid2702.203729.
6
Long COVID symptoms and duration in SARS-CoV-2 positive children - a nationwide cohort study.新冠病毒阳性儿童的长新冠症状和持续时间-一项全国性队列研究。
Eur J Pediatr. 2022 Apr;181(4):1597-1607. doi: 10.1007/s00431-021-04345-z. Epub 2022 Jan 9.
7
Prevalence of Post-COVID-19 Cough One Year After SARS-CoV-2 Infection: A Multicenter Study.新冠病毒感染一年后(post-COVID-19)咳嗽的流行情况:一项多中心研究。
Lung. 2021 Jun;199(3):249-253. doi: 10.1007/s00408-021-00450-w. Epub 2021 May 16.
8
Symptoms, complications and management of long COVID: a review.长新冠的症状、并发症及管理:综述。
J R Soc Med. 2021 Sep;114(9):428-442. doi: 10.1177/01410768211032850. Epub 2021 Jul 15.
9
Long-COVID Clinical Features and Risk Factors: A Retrospective Analysis of Patients from the STOP-COVID Registry of the PoLoCOV Study.长新冠的临床特征和风险因素:对PoLoCOV研究的STOP-COVID登记处患者的回顾性分析
Viruses. 2022 Aug 11;14(8):1755. doi: 10.3390/v14081755.
10
Persistent post-COVID-19 neuromuscular symptoms.持续的新冠后神经肌肉症状。
Muscle Nerve. 2023 Oct;68(4):350-355. doi: 10.1002/mus.27940. Epub 2023 Jul 19.

引用本文的文献

1
Long COVID-19: A Concept Analysis.长新冠:一项概念分析。
Infect Dis Rep. 2025 Jul 29;17(4):90. doi: 10.3390/idr17040090.
2
Insights on the neurocognitive mechanisms underlying hippocampus-dependent memory impairment in COVID-19.关于新冠病毒疾病中依赖海马体的记忆障碍潜在神经认知机制的见解
Sci Rep. 2025 Jun 20;15(1):20114. doi: 10.1038/s41598-025-04166-2.
3
Prevalence and characteristics of long COVID among COVID-19 survivors in Saudi Arabia: A cross-sectional study.沙特阿拉伯新冠病毒病幸存者中“长新冠”的患病率及特征:一项横断面研究
IJID Reg. 2025 Feb 28;15:100616. doi: 10.1016/j.ijregi.2025.100616. eCollection 2025 Jun.
4
Long COVID and Lung Involvement: A One-Year Longitudinal, Real-Life Study.新冠后长期症状与肺部受累:一项为期一年的纵向真实世界研究。
Medicina (Kaunas). 2025 Feb 10;61(2):304. doi: 10.3390/medicina61020304.
5
Post-COVID Neurocognitive Disorder and Its Relation with Interleukin: A Hospital-based Cross-sectional Study.新冠后神经认知障碍及其与白细胞介素的关系:一项基于医院的横断面研究。
Indian J Psychol Med. 2024 Jun 5:02537176241249373. doi: 10.1177/02537176241249373.
6
Long-term cognitive effects of COVID-19 studied with repeated neuropsychological testing.使用重复神经心理学测试研究 COVID-19 的长期认知影响。
BMJ Case Rep. 2024 Apr 17;17(4):e256711. doi: 10.1136/bcr-2023-256711.
7
Managing long COVID symptoms and accessing health services in Brazil: A grounded theory analysis.巴西长期新冠症状的管理与医疗服务获取:一项扎根理论分析。
Heliyon. 2024 Mar 22;10(7):e28369. doi: 10.1016/j.heliyon.2024.e28369. eCollection 2024 Apr 15.
8
Brain temperature and free water increases after mild COVID-19 infection.轻度 COVID-19 感染后大脑温度和自由水增加。
Sci Rep. 2024 Mar 28;14(1):7450. doi: 10.1038/s41598-024-57561-6.
9
A Case Report on Care-Seeking Type Illness Anxiety Disorder after COVID-19 Infection.新型冠状病毒感染后寻求治疗型疾病焦虑障碍病例报告
Case Rep Psychiatry. 2023 Dec 21;2023:3003499. doi: 10.1155/2023/3003499. eCollection 2023.
10
Post-COVID-19 and Irritable Bowel Syndrome: A Literature Review.新冠后肠易激综合征:文献综述。
Medicina (Kaunas). 2023 Nov 6;59(11):1961. doi: 10.3390/medicina59111961.

本文引用的文献

1
Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome?新型冠状病毒感染3个月后仍存在的症状:新冠后综合征?
ERJ Open Res. 2020 Oct 26;6(4). doi: 10.1183/23120541.00542-2020. eCollection 2020 Oct.
2
'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.'长新冠':一项针对 COVID-19 住院后持续症状、生物标志物和影像学异常的横断面研究。
Thorax. 2021 Apr;76(4):396-398. doi: 10.1136/thoraxjnl-2020-215818. Epub 2020 Nov 10.
3
Post-COVID 19 Neurological Syndrome (PCNS); a novel syndrome with challenges for the global neurology community.新冠后神经综合征(PCNS);一种给全球神经学界带来挑战的新型综合征。
J Neurol Sci. 2020 Dec 15;419:117179. doi: 10.1016/j.jns.2020.117179. Epub 2020 Oct 13.
4
COVID-19 in adult patients with pre-existing chronic cardiac, respiratory and metabolic disease: a critical literature review with clinical recommendations.患有慢性心脏、呼吸和代谢疾病的成年患者中的 COVID-19:一项带有临床建议的批判性文献综述
Trop Dis Travel Med Vaccines. 2020 Aug 28;6:16. doi: 10.1186/s40794-020-00118-y. eCollection 2020.
5
Management of post-acute covid-19 in primary care.初级保健中新冠后急性期的管理。
BMJ. 2020 Aug 11;370:m3026. doi: 10.1136/bmj.m3026.
6
Persistent Symptoms in Patients After Acute COVID-19.急性 COVID-19 后患者的持续症状。
JAMA. 2020 Aug 11;324(6):603-605. doi: 10.1001/jama.2020.12603.
7
A Review of Coronavirus Disease-2019 (COVID-19).新型冠状病毒肺炎(COVID-19)概述。
Indian J Pediatr. 2020 Apr;87(4):281-286. doi: 10.1007/s12098-020-03263-6. Epub 2020 Mar 13.