Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications, Nanjing 210023, China.
Chem Commun (Camb). 2021 Apr 21;57(31):3801-3804. doi: 10.1039/d1cc00628b. Epub 2021 Mar 19.
The mechanism underlying the strong adhesion between DNA with consecutive adenines (polyA) and Au nanoparticles (AuNPs) is experimentally and theoretically studied. We elucidate that the consecutive adenines collectively result in hydrophobic collapse in the adhesion process, which plays a pivotal role for the high adhesion affinity and specificity.
实验和理论研究了具有连续腺嘌呤（polyA）的 DNA 与金纳米粒子（AuNPs）之间强粘附的机制。我们阐明了连续的腺嘌呤共同导致粘附过程中的疏水性塌陷，这对于高粘附亲和力和特异性起着关键作用。
