Department of Chemistry, University of Iowa, Iowa City, IA 52242, USA.
Chem Commun (Camb). 2021 Apr 21;57(31):3809-3811. doi: 10.1039/d0cc08388g. Epub 2021 Mar 19.
We describe a supramolecular synthesis of a ternary cocrystal involving resveratrol and 5-fluorouracil (5-fu) with trans-bis(4-pyridyl)ethylene (bpe). We also have discovered a polymorph of a binary cocrystal involving 5-fu and bpe that originates from rare supramolecular isomerism.
我们描述了一种涉及白藜芦醇和 5-氟尿嘧啶(5-fu)与反式-双(4-吡啶基)乙烯(bpe)的三元共晶的超分子合成。我们还发现了一种涉及 5-fu 和 bpe 的二元共晶的多晶型物,它源于罕见的超分子异构现象。