Laboratorio de Ciencias AgroGenómicas, Escuela Nacional de Estudios Superiores Unidad León, Universidad Nacional Autónoma de México (ENES - León, UNAM), Blvd. UNAM 2011, León, Guanajuato, 37684, Mexico.
Laboratorio Nacional PlanTECC, Escuela Nacional de Estudios Superiores Unidad León, Universidad Nacional Autónoma de México (ENES - León, UNAM), Blvd. UNAM 2011, León, Guanajuato, 37684, Mexico.
Environ Microbiol Rep. 2021 Aug;13(4):445-457. doi: 10.1111/1758-2229.12954. Epub 2021 Jun 9.
The Oomycota phylum includes fungi-like filamentous microorganisms classified as plant pathogens. The most destructive genus within oomycetes is Phytophthora, which causes diseases in plants of economic importance in agriculture, forestry and ornamental. Phytophthora species are widespread worldwide and some of them enable adaptation to different hosts and environmental changes. The development of sexual and asexual reproductive structures and the secretion of proteins to control plant immunity are critical for the adaptative lifestyle. However, molecular mechanisms underlying the adaptation of Phytophthora to different hosts and environmental changes are poorly understood. In the last decade, the role of epigenetics has gained attention, and important evidence has demonstrated the potential role of chromatin covalent modifications, such as DNA methylation and histone acetylation/methylation, in the regulation of gene expression during Phytophthora development and plant infection. Here, we review for the first time the evidence of the potential role of chromatin covalent modifications in the lifecycle of the phytopathogenic genus Phytophthora, including virulence, and host and environment adaptation processes.
卵菌门包括被归类为植物病原体的类似真菌的丝状微生物。卵菌中的最具破坏性的属是疫霉属，它会引起农业、林业和观赏植物中具有经济重要性的植物病害。疫霉属在全球范围内广泛分布，其中一些能够适应不同的宿主和环境变化。有性和无性生殖结构的发育以及分泌蛋白质以控制植物免疫是适应生活方式的关键。然而，疫霉属适应不同宿主和环境变化的分子机制仍知之甚少。在过去十年中，表观遗传学的作用引起了人们的关注，重要证据表明，染色质共价修饰（如 DNA 甲基化和组蛋白乙酰化/甲基化）在调控疫霉属发育和植物感染过程中的基因表达方面具有潜在作用。在这里，我们首次综述了染色质共价修饰在植物病原疫霉属的生命周期中的潜在作用的证据，包括毒力、宿主和环境适应过程。
