Veterinary Epidemiology, Economics and Public Health Group, Department of Pathobiology and Population Sciences, The Royal Veterinary College, Hatfield, UK.
Ecole Inter-Etats des Sciences et Médecine Vétérinaires de Dakar, Dakar, Senegal.
Transbound Emerg Dis. 2022 May;69(3):1479-1505. doi: 10.1111/tbed.14114. Epub 2021 Jun 8.
Brucellosis is regarded as one of the highest burden zoonotic diseases to persist in many regions globally. While sustained vaccination against B. abortus in an endemic setting can markedly reduce the prevalence of large ruminant and human brucellosis and benefit local livelihoods, the implementation of effective and sustainable control programmes has often failed in the worst affected areas. In a cross-sectional study of 728 peri-urban dairy farmers in nine areas of six West and Central African countries, levels of commercialization and farm characteristics were examined alongside B. abortus seroprevalence estimates to hypothesize the most appropriate model for brucellosis vaccination delivery in each country. Demographic and economic data were collated and used to describe the farming systems currently in place. Furthermore, these data were utilized in a likelihood assessment to generate a quantitative score to hypothesize which of three private-public partnership (PPP) vaccine delivery models, that is 1) transformative, 2) transactional or 3) collaborative, would be most appropriate in each setting. The study sites had substantial differences in their levels of dairy commercialization and the farming practices employed; the heterogeneity across the study sites was evident in the conclusions of which models would be appropriate for vaccination delivery. While Lomé (Togo) had a strong indication for a transformative PPP model, Burkina Faso had strong indication for the collaborative PPP model. Of the remaining study sites, the scores were less dominant for any one model with Cameroon and Ivory Coast sites only just scoring highest on the transformative model and Senegal and Mali sites only just scoring highest on the collaborative model. Interestingly, none of the countries included in the study scored highest on the transactional model which currently is the most commonplace delivery model in the majority of sub-Saharan African countries.
布鲁氏菌病被认为是在许多全球区域持续存在的最高负担动物源性传染病之一。虽然在流行地区持续接种布鲁氏菌 abortus 疫苗可以显著降低大牲畜和人类布鲁氏菌病的流行率并有益于当地生计，但在受影响最严重的地区，有效的和可持续的控制计划的实施经常失败。在对六个西非和中非国家的九个地区的 728 名城郊奶牛养殖户进行的横断面研究中，检查了商业水平和农场特征以及布鲁氏菌 abortus 血清阳性率估计，以假设在每个国家最适合布鲁氏菌病疫苗接种的模式。收集了人口统计和经济数据，并用于描述当前存在的农业系统。此外，这些数据还用于可能性评估，以生成一个定量分数，假设三种公私合作伙伴关系 (PPP) 疫苗接种模式中的哪一种最适合每种情况，即 1）变革性，2）交易性或 3）合作性。研究地点在其乳制品商业化水平和采用的农业实践方面存在显著差异；研究地点之间的异质性在关于哪种模式最适合疫苗接种的结论中显而易见。虽然洛美（多哥）强烈表明需要变革性的公私合作伙伴关系模式，但布基纳法索强烈表明需要合作性的公私合作伙伴关系模式。在其余的研究地点中，没有一个模式得分占主导地位，喀麦隆和科特迪瓦的得分仅略高于变革性模式，塞内加尔和马里的得分仅略高于合作性模式。有趣的是，在研究中包括的国家中，没有一个国家在交易性模式上得分最高，而目前交易性模式是大多数撒哈拉以南非洲国家最常见的交付模式。
