Rudin A, Aurell M, Wilske J
Department of Endocrinology, University of Göteborg, Sweden.
Scand J Urol Nephrol. 1988;22(1):35-9. doi: 10.1080/00365599.1988.11690381.
The urinary calcium excretion has been determined in 19 patients with Bartter's syndrome and found to be significantly lower than the calcium excretion in 92 healthy subjects (1.16 +/- 0.82 vs. 4.36 +/- 2.71 mmol/24 h, p less than 0.001). There were no differences in height, weight, glomerular filtration rate, urinary sodium excretion or serum calcium concentration between the patients and the control subjects to account for the disparity in calcium excretion. In the patients, the concentrations for ionized calcium, PTH, 25-OH vitamin D and 1,25-(OH)2 vitamin D were normal. A low urinary calcium excretion appears to be a characteristic feature of Bartter's syndrome. The cause remains unexplained.
对19例巴特综合征患者的尿钙排泄情况进行了测定，发现其显著低于92名健康受试者的钙排泄量（分别为1.16±0.82与4.36±2.71 mmol/24小时，p<0.001）。患者与对照受试者在身高、体重、肾小球滤过率、尿钠排泄或血清钙浓度方面均无差异，无法解释钙排泄的差异。患者的离子钙、甲状旁腺激素、25-羟基维生素D和1,25-二羟基维生素D浓度均正常。低尿钙排泄似乎是巴特综合征的一个特征。其原因尚不清楚。
