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青少年男性脉络丛癌 1 例报告

Choroid plexus carcinoma in an adolescent male: a case report.

机构信息

Department of Paediatrics, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, 442001, India.

出版信息

J Med Case Rep. 2021 Apr 21;15(1):184. doi: 10.1186/s13256-021-02801-w.

Abstract

INTRODUCTION/BACKGROUND: Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children.

CASE PRESENTATION

We report the case of an adolescent male belonging to central India who had presented with a history of persistent headache, projectile vomiting, neck stiffness, and an episode of generalized tonic-clonic seizure. Neurological examination was suggestive of a space-occupying lesion. Further neuroimaging was suggestive of a large left-sided choroid plexus carcinoma, later confirmed on pathological examination. Gross total resection was achieved and followed by radiation therapy. His recovery was satisfactory without any major events despite suffering from such a malignancy with a poor prognosis.

CONCLUSION

In the absence of a global consensus on choroid plexus carcinoma management, our patient underwent a successful gross total resection and received postoperative radiotherapy. He made a satisfactory recovery with a further plan to review with gadolinium-enhanced neuroimaging at a later date. We conclude that, when possible, achieving gross total resection is of utmost importance.

摘要

简介/背景:尽管中枢神经系统肿瘤是儿童期最常见的恶性肿瘤病因,但脉络丛癌非常罕见,年发病率为每 10 万人中有 0.10 例。

病例介绍

我们报告了一例来自印度中部的青少年男性病例,他有持续性头痛、喷射性呕吐、颈部僵硬和全身性强直阵挛性发作的病史。神经系统检查提示有占位性病变。进一步的神经影像学检查提示左侧有一个大型脉络丛癌,后来在病理检查中得到证实。实现了大体全切除,并随后进行了放射治疗。尽管患有预后不良的恶性肿瘤,但他的恢复情况令人满意,没有发生任何重大事件。

结论

在缺乏脉络丛癌管理的全球共识的情况下,我们的患者成功地进行了大体全切除,并接受了术后放疗。他的恢复情况令人满意,计划在以后的日期用钆增强神经影像学进行进一步检查。我们的结论是,在可能的情况下,实现大体全切除至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e0/8058991/98fdc0a21066/13256_2021_2801_Fig1_HTML.jpg

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