中药注射液治疗儿童病毒性肺炎的系统评价和 Meta 分析方案
Traditional Chinese medicine injection for the treatment of viral pneumonia in children: A protocol for systematic review and meta-analysis.
机构信息
Department of Pediatrics, Shanghai Sixth People's Hospital, Shanghai, China.
出版信息
Medicine (Baltimore). 2021 Apr 23;100(16):e25506. doi: 10.1097/MD.0000000000025506.
BACKGROUND
In recent years, more and more reports are focused on the application of traditional Chinese medicine injection (TCMJ) for the treatment of viral pneumonia. There are about 200 million cases of viral pneumonia worldwide every year, half of which are children. At present, many kinds of TCMJ are created for the treatment of viral pneumonia in children, with good therapeutic effects. However, there are many kinds of TCMJ, and the treatment advantages are different, thus bringing difficulties to the selection of clinical drugs. In order to provide evidence-based evidence support for the clinical selection of TCMJ for the treatment of viral pneumonia in children, this study selected the commonly used TCMJ for clinical treatment of viral pneumonia for meta-analysis to evaluate its efficacy.
METHODS
The Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang Data, Viper information databases, Cochran library Web of Science, PubMed, MEDLINE and EMBASE will be searched. The literature will be searched, with language restriction in English and Chinese. The related reference will be retrieved as well. Two reviewers will independently extract data and perform quality assessment of included studies. Review Manager 5.3 will be applied to conduct this meta-analysis.
RESULTS
The results of this systematic review and meta-analysis will be published in a peer-reviewed journal once we finish this study.
CONCLUSIONS
This study provides reliable evidence-based evidence for the efficacy of TCMJ in the treatment of viral pneumonia in children.
ETHICS AND DISSEMINATION
We will not be allowed to publish private information from individuals. This kind of systematic review should not harm the rights of participants. No ethical approval was required. The results can be published in peer-reviewed journals or at relevant conferences.
OSF REGISTRATION NUMBER
DOI 10.17605/OSF.IO/795MB.
背景
近年来，越来越多的报告聚焦于中药注射剂（TCMJ）在病毒性肺炎治疗中的应用。全球每年约有 2 亿例病毒性肺炎病例，其中一半是儿童。目前，针对儿童病毒性肺炎，有多种 TCMJ 被创制，疗效良好。然而，TCMJ 种类繁多，治疗优势各异，这给临床药物选择带来了困难。为了为儿童病毒性肺炎的 TCMJ 临床选择提供循证医学证据支持，本研究选择了临床常用的 TCMJ 进行 meta 分析，以评估其疗效。
方法
检索中国生物医学文献数据库、中国知网、万方数据、维普信息数据库、Cochrane 图书馆 Web of Science、PubMed、MEDLINE 和 EMBASE，检索语种限定为中、英文。检索相关参考文献。由两名评价者独立提取数据并对纳入研究进行质量评价。采用 Review Manager 5.3 进行 meta 分析。
结果
本系统评价和 meta 分析的结果将在完成研究后发表在同行评议期刊上。
结论
本研究为 TCMJ 治疗儿童病毒性肺炎的疗效提供了可靠的循证医学证据。
伦理与传播
我们不会公布个人的隐私信息。这种系统评价不应损害参与者的权利。本研究无需伦理批准。研究结果可发表在同行评议期刊或相关会议上。
OSF 注册号：DOI 10.17605/OSF.IO/795MB。
Zotero 插件