Qi Xian-Mei, Luo Ya, Song Mei-Yue, Liu Ying, Shu Ting, Liu Ying, Pang Jun-Ling, Wang Jing, Wang Chen
Department of Pathophysiology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China.
Beijing University of Chinese Medicine, Beijing 100029, China.
Chin Med J (Engl). 2021 Apr 13;134(8):898-907. doi: 10.1097/CM9.0000000000001461.
Pneumoconiosis refers to a spectrum of pulmonary diseases caused by inhalation of mineral dust, usually as the result of certain occupations. The main pathological features include chronic pulmonary inflammation and progressive pulmonary fibrosis, which can eventually lead to death caused by respiratory and/or heart failure. Pneumoconiosis is widespread globally, seriously threatening global public health. Its high incidence and mortality lie in improper occupational protection, and in the lack of early diagnostic methods and effective treatments. This article reviews the epidemiology, safeguard procedures, diagnosis, and treatment of pneumoconiosis, and summarizes recent research advances and future research prospects.
尘肺病是指因吸入矿物粉尘而引起的一系列肺部疾病,通常是某些职业导致的结果。其主要病理特征包括慢性肺部炎症和进行性肺纤维化,最终可导致呼吸和/或心力衰竭死亡。尘肺病在全球范围内广泛存在,严重威胁全球公共卫生。其高发病率和死亡率在于职业防护不当,以及缺乏早期诊断方法和有效治疗手段。本文综述了尘肺病的流行病学、防护措施、诊断和治疗,并总结了近期的研究进展和未来的研究前景。