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聚 4-羟基丁酸酯可吸收屏障复合网片在腹腔镜下腹膜疝修补术中的应用。

Laparoscopic Ventral Hernia Repair with Poly-4-Hydroxybutyrate Absorbable Barrier Composite Mesh.

机构信息

Department of Surgery, College of Medicine, King Saud University, P.O. Box 7805, Riyadh 11472, Kingdom of Saudi Arabia.

Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

JSLS. 2021 Jan-Mar;25(1). doi: 10.4293/JSLS.2020.00105.

Abstract

BACKGROUND

Repair of ventral and incisional hernias (VIHR) is a common procedure, newly introduced resorbable mesh biomaterials provide an attractive option to reduce the use of permanent synthetic mesh in hernia surgery and reduce its complications. However, data on the use of slowly resorbable mesh materials remains scarce, this study aims to evaluate the use of poly-4-hydroxybutyrate/absorbable barrier composite mesh (P4HB/ABCM) in laparoscopic repair of VIHR.

METHODS

This is a retrospective study of a sequential cohort of patients undergoing laparoscopic VIHR utilizing a P4HB/ABCM mesh. Perioperative characteristics and clinical outcomes were collected.

RESULTS

In total, 26 patients including 10 females and 7 males underwent laparoscopic VIHR using P4HB/ABCM. All surgeries were performed in a single institution by the same surgeon. The average patient age was 52.6, and the mean BMI was 35.5. All patients had a clean wound classification. The average defect size was 136.4 cm. All patients were seen in clinic with a median follow-up of 28 months. We observed 4 wound seromas, and no wound infections or recurrences during the follow-up period.

CONCLUSION

Results of laparoscopic VIHR with P4HB/ABCM are favorable and encourages further studies on the role of absorbable biosynthetic mesh materials in hernia surgery.

摘要

背景

腹侧和切口疝(VIHR)的修复是一种常见的手术,新引入的可吸收网生物材料为减少疝手术中永久性合成网的使用并降低其并发症提供了一个有吸引力的选择。然而,关于使用缓慢可吸收网材料的数据仍然很少,本研究旨在评估聚-4-羟基丁酸酯/可吸收屏障复合网(P4HB/ABCM)在腹腔镜 VIHR 中的应用。

方法

这是一项使用 P4HB/ABCM 网进行腹腔镜 VIHR 的连续队列回顾性研究。收集围手术期特征和临床结果。

结果

共有 26 名患者(包括 10 名女性和 7 名男性)接受了腹腔镜 VIHR 手术,使用了 P4HB/ABCM 网。所有手术均由同一位外科医生在一家机构进行。患者平均年龄为 52.6 岁,平均 BMI 为 35.5。所有患者的伤口均为清洁伤口分类。平均缺损大小为 136.4cm。所有患者在中位随访 28 个月时均在门诊就诊。我们观察到 4 例伤口血清肿,但在随访期间无伤口感染或复发。

结论

腹腔镜 VIHR 联合使用 P4HB/ABCM 的结果是有利的,并鼓励进一步研究可吸收生物合成网材料在疝手术中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a35/8035817/2e3b492a6c55/LS-JSLS200042F001.jpg

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