Department of Surgery, Montefiore Medical Center, Bronx, NY, USA.
Department of Endocrine Surgery, Cleveland Clinic, Cleveland, OH, USA.
Surg Endosc. 2023 Oct;37(10):8080-8090. doi: 10.1007/s00464-023-10362-w. Epub 2023 Sep 5.
In the past years, there has been increasing evidence that supports the use of permanent mesh in contaminated wounds. Given this increased evidence, the indications to opt for slowly absorbable "biosynthetic" prostheses have been questioned. To address this, we compared the outcomes of slowly absorbable mesh in contaminated cases in a well-matched multicentric cohort.
The Abdominal Core Health Quality Collaborative (ACHQC) database was queried for patients undergoing elective ventral hernia repair in Centers for Disease Control (CDC)-III operations (2013-2022). We compared demographics, hernia characteristics, and postoperative outcomes among types of mesh. We used propensity score matching to adjust for sex, diabetes, body mass index, smoking status, and operative time between mesh groups. Patients within other CDC classes and those with mesh positioned elsewhere than retro-rectus/preperitoneal space were excluded.
A total of 760 patients were included in the analysis. Slowly absorbable synthetic mesh (SA) was utilized in only 7% of the cases, while permanent (P) and biologic (B) mesh in 77% and 16%, respectively. After matching, 255 patients were studied. There was no difference in surgical site occurrence (8% SA, 16% P, 10% B, p = 0.27), surgical site infection (20% SA, 17% P, 12% B p = 0.54), surgical site occurrence requiring intervention (18% SA, 13% P, 14% B p = 0.72), readmission (12% SA, 14% P, 12% B, p = 0.90), or reoperation (8% SA, 2% P, 4% B, p = 0.14) at 30 days. In patients with 1-year follow-up, there was no difference in recurrence among groups (20% SA, 26% P, 24% B p = 0.90).
Based on our findings, SA has comparable outcomes to other types of mesh, particularly when an optimal retro-rectus repair is performed.
在过去的几年中,越来越多的证据支持在污染伤口中使用永久性网片。鉴于这一证据的增加,选择缓慢吸收的“生物合成”假体的指征受到了质疑。为了解决这个问题,我们在一个匹配良好的多中心队列中比较了污染病例中缓慢吸收网片的结果。
通过疾病预防控制中心(CDC)III 类手术(2013-2022 年)在腹部核心健康质量协作(ACHQC)数据库中查询接受择期腹疝修补术的患者。我们比较了不同类型网片的患者人口统计学、疝特征和术后结果。我们使用倾向评分匹配来调整性别、糖尿病、体重指数、吸烟状态和手术时间在网片组之间的差异。排除其他 CDC 类别和网片放置在直肠后/腹膜前空间以外位置的患者。
共有 760 名患者纳入分析。只有 7%的病例使用了缓慢吸收的合成网片(SA),而永久性(P)和生物性(B)网片分别占 77%和 16%。匹配后,255 名患者进行了研究。手术部位发生率无差异(8%SA、16%P、10%B,p=0.27),手术部位感染率无差异(20%SA、17%P、12%B,p=0.54),需要干预的手术部位发生率无差异(18%SA、13%P、14%B,p=0.72),30 天再入院率无差异(12%SA、14%P、12%B,p=0.90)或再手术率无差异(8%SA、2%P、4%B,p=0.14)。在有 1 年随访的患者中,各组之间的复发率无差异(20%SA、26%P、24%B,p=0.90)。
根据我们的发现,SA 的结果与其他类型的网片相当,特别是当进行最佳的直肠后修复时。