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Fe-黄芩素纳米粒子的简便合成及其用于光热/化学动力学治疗的研究,加速了 Fe/Fe 的转化。

Facile synthesis of Fe-baicalein nanoparticles for photothermal/chemodynamic therapy with accelerated Fe/Fe conversion.

机构信息

State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, P. R. China.

出版信息

J Mater Chem B. 2021 Apr 21;9(15):3295-3299. doi: 10.1039/d1tb00200g. Epub 2021 Apr 12.


DOI:10.1039/d1tb00200g
PMID:33881434
Abstract

Fe-baicalein-polyethylene glycol (Fe-BaP) nanoparticles were synthesized by a room temperature wet chemical method via coordination between Fe and baicalein. Fe-BaP possessed high photothermal conversion efficiency (η = 45.6%) and excellent antitumor efficacy was achieved with the synergistic photothermal/chemodynamic tumor therapy.

摘要

Fe-黄芩素-聚乙二醇(Fe-BaP)纳米粒子通过 Fe 和黄芩素之间的配位作用,采用室温湿化学方法合成。Fe-BaP 具有高光热转换效率(η = 45.6%),并通过光热/化学动力学协同肿瘤治疗实现了优异的抗肿瘤疗效。

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[4]
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