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[肺癌中自然杀伤活性及淋巴细胞对组织抗原的致敏作用]

[Natural killer activity and sensitization of the lymphocytes to tissue antigens in lung cancer].

作者信息

Red'ko A A, Malygin A M, Dvaladze N A, Pleskach V A, Kutushev F Kh

出版信息

Vestn Khir Im I I Grek. 1988 Feb;140(2):12-5.

PMID:3388698
Abstract

A decreased natural killer activity was observed in patients with lung cancer as the disease progressed. Surgical intervention results in its elevation at the IIId stage, while the application of cytostatics or irradiation are efficient at the IIId and IInd stages. Pronounced sensibilization of the peripheral blood lymphocytes in cancer patients to normal and cancer tissue antigens was demonstrated with the help of the leukocyte adhesion inhibition test.

摘要

随着疾病进展,肺癌患者的自然杀伤活性降低。手术干预可使Ⅲ期患者的该活性升高,而在Ⅲ期和Ⅱ期应用细胞抑制剂或放疗则有效。借助白细胞黏附抑制试验证实,癌症患者外周血淋巴细胞对正常组织和癌组织抗原出现明显的致敏现象。

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