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有腿可撑:创伤中心指定与严重下肢损伤患者保肢率的关联。

A Leg to Stand on: Trauma Center Designation and Association with Rate of Limb Salvage in Patients Suffering Severe Lower Extremity Injury.

机构信息

Department of Surgery, Loyola University Chicago, Maywood; Burn and Shock Trauma Research Institute, Loyola University Chicago, Maywood.

Department of Surgery, Loyola University Chicago, Maywood; Burn and Shock Trauma Research Institute, Loyola University Chicago, Maywood.

出版信息

J Am Coll Surg. 2021 Jul;233(1):120-129.e5. doi: 10.1016/j.jamcollsurg.2021.04.012. Epub 2021 Apr 20.

Abstract

BACKGROUND

Mangled extremities are one of the most difficult injuries for trauma surgeons to manage. We compare limb salvage rates for a limb-threatening lower extremity injuries managed at Level I vs Level II trauma centers (TCs).

STUDY DESIGN

We identified all adult patients with a limb-threatening injury who underwent primary amputation or limb salvage (LS) using the American College of Surgeons (ACS) Trauma Quality Improvement Program database at ACS Level I vs II TCs between 2007 and 2017. A limb-threatening injury was defined as an open tibial fracture with concurrent arterial injury (Gustilo type IIIc). Multivariable analysis and propensity score matching were performed to minimize confounding by indication.

RESULTS

There were 712 records for analysis; 391 (54.9%) LS performed and 321 (45.1%) underwent amputation. The rate of LS was statistically higher among patients treated at Level I TCs vs those treated at Level II TCs (47.4% vs 34.8%; p = 0.01). Patients with penetrating injuries (13% vs 9.5%; p = 0.046) and tibial/peroneal artery injury (72.9% vs 50.4%; p < 0.001), as opposed to popliteal artery injury (30.8% vs 58.8%; p < 0.001), were more likely to have LS. The risk-adjusted odds of LS was 3.13 times higher at Level I TCs vs Level II TCs (95% CI, 1.59 to 6.34; p = 0.001). Limb salvage rates were significantly higher at Level I TCs compared with Level II TCs (53.0% vs 34.8%; p = 0.004), even after propensity matching.

CONCLUSIONS

In patients with a mangled extremity, limb salvage rates are 50% higher at Level I TCs compared with Level II TCs, independent of case mix and injury severity.

摘要

背景

对于创伤外科医生来说,处理严重创伤的四肢是最困难的。我们比较了在一级和二级创伤中心(TC)治疗的威胁肢体的下肢损伤的保肢率。

研究设计

我们使用美国外科医师学院(ACS)创伤质量改进计划数据库,在 2007 年至 2017 年期间,在 ACS 一级和二级 TC 中确定了所有接受主要截肢或保肢(LS)治疗的威胁肢体的成年患者。威胁肢体的损伤定义为伴有动脉损伤的开放性胫骨骨折(Gustilo Ⅲc 型)。进行多变量分析和倾向评分匹配,以最大限度地减少混杂因素。

结果

共分析了 712 份记录;391 例(54.9%)行 LS,321 例(45.1%)行截肢。一级 TC 治疗的患者 LS 率明显高于二级 TC 治疗的患者(47.4% vs 34.8%;p=0.01)。穿透性损伤患者(13% vs 9.5%;p=0.046)和胫骨/腓动脉损伤患者(72.9% vs 50.4%;p<0.001),而非腘动脉损伤患者(30.8% vs 58.8%;p<0.001)更有可能行 LS。一级 TC 与二级 TC 的 LS 风险调整比值为 3.13(95%CI,1.59 至 6.34;p=0.001)。与二级 TC 相比,一级 TC 的保肢率明显更高(53.0% vs 34.8%;p=0.004),即使在倾向评分匹配后也是如此。

结论

在严重创伤的四肢患者中,一级 TC 的保肢率比二级 TC 高 50%,与病例组合和损伤严重程度无关。

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本文引用的文献

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Multiple imputation in trauma disparity research.创伤差异研究中的多重插补。
J Surg Res. 2011 Jan;165(1):e37-41. doi: 10.1016/j.jss.2010.09.025. Epub 2010 Oct 16.

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