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创伤差异研究中的多重插补。

Multiple imputation in trauma disparity research.

机构信息

Department of Surgery, Howard University College of Medicine, Washington, DC 20060, USA.

出版信息

J Surg Res. 2011 Jan;165(1):e37-41. doi: 10.1016/j.jss.2010.09.025. Epub 2010 Oct 16.

Abstract

BACKGROUND

Missing data has remained a major disparity in trauma outcomes research due to missing race and insurance data. Multiple imputation (M.IMP) has been recommended as a solution to deal with this major drawback.

STUDY DESIGN

Using the National Data Trauma Bank (NTDB) as an example, a complete dataset was developed by deleting cases with missing data across variables of interest. An incomplete dataset was then created from the complete set using random deletion to simulate the original NTDB, followed by five M.IMP rounds to generate a final imputed dataset. Identical multivariate analyses were performed to investigate the effect of race and insurance on mortality in both datasets.

RESULTS

Missing data proportions for known trauma mortality covariates were as follows: age-4%, gender-0.4%, race-8%, insurance-17%, injury severity score-6%, revised trauma score-20%, and trauma type-3%. The M.IMP dataset results were qualitatively similar to the original dataset.

CONCLUSION

M.IMP is a feasible tool in NTDB for handling missing race and insurance data.

摘要

背景

由于缺少种族和保险数据,缺失数据仍然是创伤结局研究中的一个主要差异。推荐使用多重插补(M.IMP)来解决这个主要缺点。

研究设计

以国家创伤数据库(NTDB)为例,通过删除感兴趣变量的缺失数据,开发了一个完整的数据集。然后从完整的数据集使用随机删除来创建一个不完整的数据集,以模拟原始的 NTDB,然后进行五轮 M.IMP 以生成最终的插补数据集。对两个数据集进行了相同的多变量分析,以研究种族和保险对死亡率的影响。

结果

已知创伤死亡率协变量的缺失数据比例如下:年龄-4%,性别-0.4%,种族-8%,保险-17%,损伤严重程度评分-6%,修订创伤评分-20%,创伤类型-3%。M.IMP 数据集的结果与原始数据集定性相似。

结论

M.IMP 是 NTDB 中处理缺失种族和保险数据的一种可行工具。

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