Haghighat Abbas, Pourarz Sobhan, Ghazizadeh Maryam, Talebzadeh Zahra
Department of Oral and Maxillofacial Surgery, Dental Implants Research Center, School of Dentistry, Isfahan University of Medical Sciences, Kermanshah, Iran.
Department of Oral and Maxillofacial Surgery, School of Dentistry, Isfahan University of Medical Sciences, Kermanshah, Iran.
Dent Res J (Isfahan). 2020 Dec 10;17(6):480-483. eCollection 2020 Nov-Dec.
Tricho-dento-osseous (TDO) syndrome is a multisystem congenital disorder that is known by bone, skin, and hair abnormalities. Primitive studies show different varieties of manifestations related to this disorder, which involve sclerotic bones, nail involvement, enamel hypoplasia, mandibular prognathism, and taurodontism. Although exploring different TDO cases revealed genetic mutations in all of them, they have many variations in phenotypic view. In this study, we report a case whose primary diagnosis was alopecia and came for extraction of her third molars, but after clinical and radiographic examination, it was found that the cause of her disease was something different.
毛发-牙齿-骨(TDO)综合征是一种多系统先天性疾病,以骨骼、皮肤和毛发异常为特征。早期研究显示该疾病有不同类型的表现,包括骨质硬化、指甲受累、釉质发育不全、下颌前突和牛牙症。尽管对不同的TDO病例进行研究发现所有病例均存在基因突变,但它们在表型上有许多差异。在本研究中,我们报告了一例最初诊断为脱发并前来拔除第三磨牙的病例,但经过临床和影像学检查后,发现其病因并非如此。