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不明原因的闭经和β人绒毛膜促性腺激素升高：绒毛膜癌的一个意外部位。

Amenorrhea and elevated βhuman chorionic gonadotropin of unknown origin: An unexpected location of choriocarcinoma.

作者信息

Ben Abdallah Ichrak, Mlika Mona, Berrazega Yosra, Mejri Nesrine, Rachdi Haifa, El Benna Houda, Daoud Nouha, Laabidi Soumaya, Mezni Faouzi, Boussen Hamouda

机构信息

Université Tunis EL Manar, Faculté de Médecine de Tunis, Department of Medical Oncology, Abderrahmane Mami Hospital, Tunisia.

Université Tunis EL Manar, Faculté de Médecine de Tunis, Department of Pathology, Abderrahmane Mami Hospital, Tunisia.

出版信息

Gynecol Oncol Rep. 2021 Mar 13;36:100746. doi: 10.1016/j.gore.2021.100746. eCollection 2021 May.

DOI:10.1016/j.gore.2021.100746
PMID:33889701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8047451/
Abstract

Choriocarcinoma is a rare malignancy originating from trophoblastic cells that is known to arise from the placenta. In this report, we describe the case of a 28-year-old female who consulted for amenorrhea and elevated βhCG mimicking a pregnancy of an unknown location, which ultimately turned out to be primary choriocarcinoma of the lung.

摘要

绒毛膜癌是一种罕见的恶性肿瘤，起源于已知源自胎盘的滋养层细胞。在本报告中，我们描述了一名28岁女性的病例，她因闭经和βhCG升高前来就诊，表现类似异位妊娠，最终确诊为原发性肺绒毛膜癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbc/8047451/937299dfe829/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbc/8047451/52bf983e6637/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbc/8047451/94eeb87847bf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbc/8047451/937299dfe829/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbc/8047451/52bf983e6637/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbc/8047451/94eeb87847bf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fbc/8047451/937299dfe829/gr3.jpg

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Gynecol Oncol Rep. 2021 Mar 13;36:100746. doi: 10.1016/j.gore.2021.100746. eCollection 2021 May.
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本文引用的文献

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A Case Report of Primary Pulmonary Choriocarcinoma in a Man: Successful Combination of Surgery and Chemotherapy.一名男性原发性肺绒毛膜癌病例报告：手术与化疗的成功联合应用
Case Rep Oncol. 2020 Jul 30;13(2):923-928. doi: 10.1159/000508744. eCollection 2020 May-Aug.
2
Precision genotyping diagnosis of lung tumors with trophoblastic morphology in young women.年轻女性具有滋养层形态的肺肿瘤的精准基因分型诊断。
Mod Pathol. 2019 Sep;32(9):1271-1280. doi: 10.1038/s41379-019-0275-z. Epub 2019 Apr 25.
3
A Rare Case of Metastatic Choriocarcinoma of Lung Origin.
一例罕见的肺源性转移性绒毛膜癌病例。
Case Rep Pulmonol. 2017;2017:4649813. doi: 10.1155/2017/4649813. Epub 2017 Dec 7.
4
Primary pulmonary choriocarcinoma.原发性肺绒毛膜癌
Radiol Oncol. 2016 Jun 24;51(1):1-7. doi: 10.1515/raon-2016-0038. eCollection 2017 Mar 1.
5
An unusual case of primary choriocarcinoma of the lung.一例罕见的原发性肺绒毛膜癌病例。
BMC Surg. 2013;13 Suppl 2(Suppl 2):S33. doi: 10.1186/1471-2482-13-S2-S33. Epub 2013 Oct 8.
6
Gestational trophoblastic disease: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.妊娠滋养细胞疾病：ESMO诊断、治疗及随访临床实践指南
Ann Oncol. 2013 Oct;24 Suppl 6:vi39-50. doi: 10.1093/annonc/mdt345. Epub 2013 Sep 1.
7
Incidental placental choriocarcinoma in a term pregnancy: a case report.足月妊娠时偶然发现的胎盘绒毛膜癌：一例报告
J Med Case Rep. 2008 Oct 16;2:330. doi: 10.1186/1752-1947-2-330.
8
Trends in gestational choriocarcinoma: a 27-year perspective.妊娠性绒毛膜癌的趋势：27年的观察视角
Obstet Gynecol. 2003 Nov;102(5 Pt 1):978-87. doi: 10.1016/s0029-7844(03)00669-0.
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Choriocarcinoma and partial hydatidiform moles.绒毛膜癌和部分性葡萄胎。
Lancet. 2000 Jul 1;356(9223):36-9. doi: 10.1016/S0140-6736(00)02432-6.