Bielow Tobias, Blank Valentin, Opitz Sabine, Gößmann Holger, Hecker Martin, Seehofer Daniel, Lübbert Christoph, Karlas Thomas
Division of Gastroenterology, Department of Medicine II, University Hospital Leipzig, Leipzig, Germany.
Institute of Pathology, Department of Diagnostics, University Hospital Leipzig, Leipzig, Germany.
Ultrasound Int Open. 2021 Apr;7(1):E2-E5. doi: 10.1055/a-1471-6907. Epub 2021 Apr 20.
Invasive liver abscess syndrome (ILAS) is caused by strains of hypervirulent Klebsiella pneumoniae (hvKp) and has emerged as the leading cause of liver abscesses in immuno-competent patients (L.K. Siu et al. Lancet Infect Dis 2012; 12: 881-87). ILAS is frequently associated with metastatic spread including the eyes, lungs, and the central nervous system. The morbidity and mortality of affected patients are increased compared to liver abscesses of other origin, especially in cases with concomitant diabetes mellitus (J. E. Choby et al. J Intern Med 2020; 287(3): 283-300). Immediate diagnosis and early intervention are essential for an optimal outcome. Therefore, ultrasound plays a crucial role if hvKp is suspected. However, experience with the characteristics of such abscesses on contrast-enhanced ultrasound (CEUS) is very limited.
侵袭性肝脓肿综合征（ILAS）由高毒力肺炎克雷伯菌（hvKp）菌株引起，已成为免疫功能正常患者肝脓肿的主要病因（L.K. Siu等人，《柳叶刀·传染病》，2012年；12：881 - 87）。ILAS常伴有包括眼部、肺部和中枢神经系统在内的转移扩散。与其他病因引起的肝脓肿相比，受影响患者的发病率和死亡率更高，尤其是在合并糖尿病的病例中（J.E. Choby等人，《内科医学杂志》，2020年；287(3)：283 - 300）。立即诊断和早期干预对于获得最佳治疗效果至关重要。因此，如果怀疑是hvKp感染，超声检查起着关键作用。然而，关于此类脓肿在对比增强超声（CEUS）下特征的经验非常有限。
