Larionov G M
Zh Mikrobiol Epidemiol Immunobiol. 1988 Mar(3):36-40.
The growth and death of Pseudomonas pseudomallei, the causative agent of melioidosis, in the soil and the antigenic properties of this microorganism in the soil, in culture media, and in the body of animals have been studied. As revealed in this study, P. pseudomallei can grow in nonsterile soil substrates without the loss of virulence and changes in its antigenic structure. In the body of animals this microorganism rapidly adapts its virulence to host species by the transformation of its antigenic structure. The pathogenicity factors of P. pseudomallei are mainly thermolabile antigens, probably exoenzymes. This microorganism has been shown to have close ecological relations with abiotic environmental objects. The author suggests that the type of relationship between saprophytic microorganisms acting as causative agents of diseases and warm-blooded hosts should be characterized as pseudoparasitic.
类鼻疽病病原体——类鼻疽假单胞菌在土壤中的生长与死亡情况，以及该微生物在土壤、培养基和动物体内的抗原特性已得到研究。本研究表明，类鼻疽假单胞菌能够在非无菌土壤基质中生长，而不丧失其毒力，其抗原结构也不会发生变化。在动物体内，这种微生物通过改变其抗原结构，迅速使其毒力适应宿主物种。类鼻疽假单胞菌的致病因子主要是热不稳定抗原，可能是外酶。已证明这种微生物与非生物环境物体存在密切的生态关系。作者认为，作为疾病病原体的腐生微生物与温血宿主之间的关系类型应被描述为假寄生关系。
