Peters M K, Piven' N N, Iliukhin V I, Barkov A M
Zh Mikrobiol Epidemiol Immunobiol. 1983 Aug(8):47-50.
The comparative analysis of the antigenic spectra of Pseudomonas pseudomallei museum and subcultured strains, carried out by the method of immunoelectrophoresis, has revealed that, along with an essential increase in the virulence of P. pseudomallei for white mice and changes in the morphology of colonies, a decrease in the amount of detected precipitinogens occurs in the process of subculturing. The immunoelectrophoregrams of the subcultured variants show the absence of antigens 5, 6 and the simultaneous increase of the production of antigen 8, one of the components of mucoid (in the pseudocapsule).
通过免疫电泳法对类鼻疽杆菌保藏菌株和传代培养菌株的抗原谱进行比较分析后发现，随着类鼻疽杆菌对小白鼠毒力的显著增强以及菌落形态的变化，传代培养过程中检测到的沉淀原数量减少。传代培养变体的免疫电泳图谱显示，抗原5、6缺失，同时作为黏液样（在假荚膜中）成分之一的抗原8的产生量增加。
