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[人工智能与大数据时代视神经乳头疾病的诊断]

[Diagnostics of diseases of the optic nerve head in times of artificial intelligence and big data].

作者信息

Diener R, Treder M, Eter N

机构信息

Klinik für Augenheilkunde, Universitätsklinikum Münster, Domagkstr. 15, 48149, Münster, Deutschland.

出版信息

Ophthalmologe. 2021 Sep;118(9):893-899. doi: 10.1007/s00347-021-01385-6. Epub 2021 Apr 22.

DOI:10.1007/s00347-021-01385-6
PMID:33890129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8062109/
Abstract

BACKGROUND

The use of artificial intelligence (AI) interesting for automated image segmentation, analysis and classification, among others and has already been described for various fields of ophthalmology.

OBJECTIVE

This manuscript provides an overview of current approaches and advances in the application of big data and AI in various diseases of the optic nerve head.

MATERIAL AND METHODS

A PubMed search was performed. Studies were searched for that answered clinical questions using big data approaches or classical machine learning methods in the analysis of multimodal imaging of the optic nerve head.

RESULTS

Big data can help to answer clinical questions in common diseases such as glaucoma. The AI is applied for the segmentation of multimodal imaging of the optic nerve head as well as for the classification of diseases, such as glaucoma or optic disc edema on this imaging data.

CONCLUSION

With the help of big data and AI, relationships can be recognized more easily and the diagnostics and course assessment of diseases of the optic nerve head can be facilitated or automated. A prerequisite for clinical application is a CE marking as a medical device in Europe and approval by the Food and Drug Administration in the USA.

摘要

背景

人工智能(AI)在自动图像分割、分析和分类等方面的应用颇受关注,并且已经在眼科的各个领域有所描述。

目的

本文综述了大数据和人工智能在视神经乳头各种疾病应用中的当前方法和进展。

材料与方法

进行了PubMed检索。检索了使用大数据方法或经典机器学习方法分析视神经乳头多模态成像以回答临床问题的研究。

结果

大数据有助于回答青光眼等常见疾病的临床问题。人工智能应用于视神经乳头多模态成像的分割以及基于此成像数据的疾病分类,如青光眼或视盘水肿。

结论

借助大数据和人工智能,可以更轻松地识别关系,促进或自动化视神经乳头疾病的诊断和病程评估。临床应用的一个先决条件是在欧洲作为医疗器械获得CE标志,并在美国获得食品药品监督管理局的批准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8216/8062109/359d94cf7d6d/347_2021_1385_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8216/8062109/ba86f00faa31/347_2021_1385_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8216/8062109/cf3d55d6302e/347_2021_1385_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8216/8062109/359d94cf7d6d/347_2021_1385_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8216/8062109/ba86f00faa31/347_2021_1385_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8216/8062109/cf3d55d6302e/347_2021_1385_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8216/8062109/359d94cf7d6d/347_2021_1385_Fig3_HTML.jpg

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本文引用的文献

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Towards label-free 3D segmentation of optical coherence tomography images of the optic nerve head using deep learning.利用深度学习实现对视神经乳头光学相干断层扫描图像的无标记三维分割
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Joint disc and cup segmentation based on recurrent fully convolutional network.基于递归全卷积网络的关节盘和关节盂分割。
PLoS One. 2020 Sep 21;15(9):e0238983. doi: 10.1371/journal.pone.0238983. eCollection 2020.
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Artificial Intelligence Mapping of Structure to Function in Glaucoma.
人工智能在青光眼结构与功能关系研究中的应用
Transl Vis Sci Technol. 2020 Mar 30;9(2):19. doi: 10.1167/tvst.9.2.19. eCollection 2020 Mar.
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Application of the Sight Outcomes Research Collaborative Ophthalmology Data Repository for Triaging Patients With Glaucoma and Clinic Appointments During Pandemics Such as COVID-19.在 COVID-19 等大流行期间,Sight Outcomes Research Collaborative Ophthalmology Data Repository 在青光眼患者分诊和诊所预约中的应用。
JAMA Ophthalmol. 2020 Sep 1;138(9):974-980. doi: 10.1001/jamaophthalmol.2020.2974.
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[Artificial intelligence in management of macular edema : Opportunities and challenges].[人工智能在黄斑水肿管理中的应用:机遇与挑战]
Ophthalmologe. 2020 Oct;117(10):989-992. doi: 10.1007/s00347-020-01110-9.
6
Association of Systemic Hypertension With Primary Open-angle Glaucoma: A Population-based Case-Control Study.系统性高血压与原发性开角型青光眼的相关性:一项基于人群的病例对照研究。
Am J Ophthalmol. 2020 Oct;218:99-104. doi: 10.1016/j.ajo.2020.04.020. Epub 2020 Apr 28.
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Artificial Intelligence to Detect Papilledema from Ocular Fundus Photographs.人工智能检测眼底照片中的视乳头水肿。
N Engl J Med. 2020 Apr 30;382(18):1687-1695. doi: 10.1056/NEJMoa1917130. Epub 2020 Apr 14.
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Efficacy for Differentiating Nonglaucomatous Versus Glaucomatous Optic Neuropathy Using Deep Learning Systems.使用深度学习系统鉴别非青光眼性与青光眼性视神经病变的疗效。
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Assessment of a Segmentation-Free Deep Learning Algorithm for Diagnosing Glaucoma From Optical Coherence Tomography Scans.基于无分割深度学习算法的光学相干断层扫描图像青光眼诊断评估。
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