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东非地区医疗机构分娩的合并患病率及相关因素:混合效应逻辑回归分析

Pooled prevalence and associated factors of health facility delivery in East Africa: Mixed-effect logistic regression analysis.

作者信息

Tesema Getayeneh Antehunegn, Tessema Zemenu Tadesse

机构信息

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

PLoS One. 2021 Apr 23;16(4):e0250447. doi: 10.1371/journal.pone.0250447. eCollection 2021.

DOI:10.1371/journal.pone.0250447
PMID:33891647
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8064605/
Abstract

BACKGROUND

Many mothers still give birth outside a health facility in Sub-Saharan Africa particularly in East African countries. Though there are studies on the prevalence and associated factors of health facility delivery, as to our search of literature there is limited evidence on the pooled prevalence and associated factors of health facility delivery in East Africa. This study aims to examine the pooled prevalence and associated factors of health facility delivery in East Africa based on evidence from Demographic and Health Surveys.

METHODS

A secondary data analysis was conducted based on the most recent Demographic and Health Surveys (DHSs) conducted in the 12 East African countries. A total weighted sample of 141,483 reproductive-age women who gave birth within five years preceding the survey was included. All analyses presented in this paper were weighted for the sampling probabilities and non-response using sampling weight (V005), primary sampling unit (V023), and strata (V021). The analysis was done using STATA version 14 statistical software, and the pooled prevalence of health facility delivery with a 95% Confidence Interval (CI) was presented using a forest plot. For associated factors, the Generalized Linear Mixed Model (GLMM) was fitted to consider the hierarchical nature of the DHS data. The Intra-class Correlation Coefficient (ICC), Median Odds Ratio (MOR), and Likelihood Ratio (LR)-test were done to assess the presence of a significant clustering effect. Besides, deviance (-2LLR) was used for model comparison since the models were nested models. Variables with a p-value of less than 0.2 in the bivariable mixed-effect binary logistic regression analysis were considered for the multivariable analysis. In the multivariable mixed-effect analysis, the Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) were reported to declare the strength and significance of the association between the independent variable and health facility delivery.

RESULTS

The proportion of health facility delivery in East Africa was 87.49% [95% CI: 87.34%, 87.64%], ranged from 29% in Ethiopia to 97% in Mozambique. In the Mixed-effect logistic regression model; country, urban residence [AOR = 2.08, 95% CI: 1.96, 2.17], primary women education [AOR = 1.61, 95% CI: 1.55, 1.67], secondary education and higher [AOR = 2.96, 95% CI: 2.79, 3.13], primary husband education [AOR = 1.19, 95% CI: 1.14, 1.24], secondary husband education [AOR = 1.38, 95% CI: 1.31, 1.45], being in union [AOR = 1.23, 95% CI: 1.18, 1.27], having occupation [AOR = 1.11, 95% CI: 1.07, 1.15], being rich [AOR = 1.36, 95% CI: 1.30, 1.41], and middle [AOR = 2.14, 95% CI: 2.04, 2.23], health care access problem [AOR = 0.76, 95% CI: 0.74, 0.79], having ANC visit [AOR = 1.54, 95% CI: 1.49, 1.59], parity [AOR = 0.56, 95% CI: 0.55, 0.61], multiple gestation [AOR = 1.83, 95% CI: 1.67, 2.01] and wanted pregnancy [AOR = 1.19, 95% CI: 1.13, 1.25] were significantly associated with health facility delivery.

CONCLUSION

This study showed that the proportion of health facility delivery in East African countries is low. Thus, improved access and utilization of antenatal care can be an effective strategy to increase health facility deliveries. Moreover, encouraging women through education is recommended to increase health facility delivery service utilization.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfcd/8064605/75c1a89eabd6/pone.0250447.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfcd/8064605/75c1a89eabd6/pone.0250447.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfcd/8064605/75c1a89eabd6/pone.0250447.g001.jpg
摘要

背景

在撒哈拉以南非洲地区,尤其是东非国家,许多产妇仍在医疗机构以外的地方分娩。尽管已有关于医疗机构分娩的患病率及相关因素的研究,但就我们对文献的检索而言,关于东非地区医疗机构分娩的合并患病率及相关因素的证据有限。本研究旨在基于人口与健康调查的证据,探讨东非地区医疗机构分娩的合并患病率及相关因素。

方法

基于在12个东非国家进行的最新人口与健康调查开展二次数据分析。纳入了在调查前五年内分娩的141,483名育龄妇女的总加权样本。本文呈现的所有分析均使用抽样权重(V005)、初级抽样单位(V023)和分层(V021)对抽样概率和无应答情况进行加权。使用STATA 14版统计软件进行分析,并通过森林图呈现医疗机构分娩的合并患病率及95%置信区间(CI)。对于相关因素,采用广义线性混合模型(GLMM)来考虑人口与健康调查数据的分层性质。进行组内相关系数(ICC)、中位数优势比(MOR)和似然比(LR)检验以评估显著聚类效应的存在。此外,由于模型为嵌套模型,使用偏差(-2LLR)进行模型比较。在双变量混合效应二元逻辑回归分析中p值小于0.2的变量被纳入多变量分析。在多变量混合效应分析中,报告调整优势比(AOR)及95%置信区间(CI)以阐明自变量与医疗机构分娩之间关联的强度和显著性。

结果

东非地区医疗机构分娩的比例为87.49% [95% CI:87.34%,87.64%],范围从埃塞俄比亚的29%到莫桑比克的97%。在混合效应逻辑回归模型中;国家、城市居住情况 [AOR = 2.08,95% CI:1.96,2.17]、女性初等教育程度 [AOR = 1.61,95% CI:1.55,1.67]、中等及以上教育程度 [AOR = 2.96,95% CI:2.79,3.13]、丈夫初等教育程度 [AOR = 1.19,95% CI:1.14,1.24]、丈夫中等教育程度 [AOR = 1.38,95% CI:1.31,1.45]、处于婚姻关系 [AOR = 1.23,95% CI:1.18,1.27]、有职业 [AOR = 1.11,95% CI:1.07,1.15]、富裕 [AOR = 1.36,95% CI:1.30,1.41] 和中等收入 [AOR = 2.14,95% CI:2.04,2.23]、医疗保健获取问题 [AOR = 0.76,95% CI:0.74,0.79]、进行过产前检查 [AOR = 1.54,95% CI:1.49,1.59]、产次 [AOR = 0.56,95% CI:0.55,0.61]、多胎妊娠 [AOR = 1.83,95% CI:1.67,2.01] 和意愿妊娠 [AOR = 1.19,95% CI:1.13,1.25] 与医疗机构分娩显著相关。

结论

本研究表明东非国家医疗机构分娩的比例较低。因此,改善产前保健的可及性和利用率可能是增加医疗机构分娩的有效策略。此外,建议通过教育鼓励妇女以提高医疗机构分娩服务的利用率。

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