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COVID-19 大流行对 50 至 70 岁女性全球健康的影响。

Effects of the COVID-19 pandemic on the global health of women aged 50 to 70 years.

机构信息

Department of Internal Medicine, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil.

Department of Food and Nutrition, Faculty of Pharmaceutical Sciences of Araraquara, Paulista State University, SP, Brazil.

出版信息

Exp Gerontol. 2021 Jul 15;150:111349. doi: 10.1016/j.exger.2021.111349. Epub 2021 Apr 21.

Abstract

AIM/BACKGROUND: The most recent pandemic caused by the new coronavirus disease (COVID-19) urged dramatic changes in people's lives. Potentially, the COVID-19 pandemic affects physical and mental health as well as behavioral and social aspects. However, the direct impacts of the COVID-19 pandemic on health-related parameters are not yet known. The present study aimed to evaluate the effect of 16 weeks during the COVID-19 pandemic on health-related parameters of physically inactive women aged 50 to 70 years.

METHODS

Thirty-four physically inactive women participated in the study. We performed tests to evaluate aerobic capacity and muscle strength, anthropometric measurements, blood pressure (BP), blood parameters, diet, and physical activity levels. All evaluations were carried out before and 16 weeks after the initial phase of the COVID-19 pandemic in Brazil (i.e., from March to July 2020).

RESULTS

Systolic BP (p < .0001; effect size (ES) = 0.62), diastolic BP (p < .0001; ES = 0.71), grip strength of the right (p < .05; ES = 0.43) and left hand (p < .05; ES = 0.49), performance in six-minute walk test (p < .05; ES = 0.46), free time physical activity levels (p < .05; ES = 0.40), domestic physical activity levels (p < .05; ES = 0.39), platelet count (p < .0001; ES = 0.48), and mean corpuscular hemoglobin concentration (p < .0001; ES = 1.14) reduced in comparison to the period before the pandemic. In contrast, glycated hemoglobin levels (p < .0001; ES = 0.77), triglycerides (p < .05; ES = 0.40), and insulin levels (p < .05; ES = 0.60) increased in comparison to the period before the pandemic.

CONCLUSION

The COVID-19 pandemic negatively impacted the general health status of physically inactive women aged 50 to 70, potentially increasing their susceptibility to comorbidities, such as type 2 diabetes and hypertriglyceridemia.

摘要

目的/背景:由新型冠状病毒病(COVID-19)引起的最近一次大流行极大地改变了人们的生活。新型冠状病毒肺炎可能会影响身心健康以及行为和社会方面。然而,COVID-19 大流行对健康相关参数的直接影响尚不清楚。本研究旨在评估 COVID-19 大流行期间的 16 周对 50 至 70 岁身体不活跃的女性健康相关参数的影响。

方法

34 名身体不活跃的女性参加了这项研究。我们进行了测试来评估有氧能力和肌肉力量、人体测量学测量、血压(BP)、血液参数、饮食和身体活动水平。所有评估均在巴西 COVID-19 大流行的初始阶段(即 2020 年 3 月至 7 月)前后 16 周进行。

结果

收缩压(p <.0001;效应量(ES)= 0.62)、舒张压(p <.0001;ES = 0.71)、右手握力(p <.05;ES = 0.43)和左手握力(p <.05;ES = 0.49)、六分钟步行测试(p <.05;ES = 0.46)、自由时间身体活动水平(p <.05;ES = 0.40)、家务身体活动水平(p <.05;ES = 0.39)、血小板计数(p <.0001;ES = 0.48)和平均红细胞血红蛋白浓度(p <.0001;ES = 1.14)与大流行前相比均降低。相比之下,糖化血红蛋白水平(p <.0001;ES = 0.77)、甘油三酯(p <.05;ES = 0.40)和胰岛素水平(p <.05;ES = 0.60)与大流行前相比均升高。

结论

COVID-19 大流行对 50 至 70 岁身体不活跃的女性的整体健康状况产生了负面影响,可能会增加她们患 2 型糖尿病和高甘油三酯血症等合并症的易感性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d293/8058051/db886619840a/gr1_lrg.jpg

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