Jacques P F, Hartz S C, Chylack L T, McGandy R B, Sadowski J A
USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111.
Am J Clin Nutr. 1988 Jul;48(1):152-8. doi: 10.1093/ajcn/48.1.152.
As part of an exploratory study of nutrition and senile cataract relationships between biochemical markers of nutritional status and senile cataract were examined in 112 subjects aged 40-70 y. Seventy-seven subjects had a cataract in at least one lens. Blood levels were determined for total carotenoids, vitamin A, vitamin D, vitamin E, vitamin C, riboflavin, thiamin, vitamin B-6, zinc, copper, selenium, and magnesium. Subjects were grouped into quintiles for each nutrient. Logistic regression was used to estimate the odds ratios (ORs) for cataract among subjects in the highest quintile and the middle three quintiles relative to subjects in the lowest quintile. ORs were adjusted for age, sex, race, and presence of diabetes. Results suggest that risk of cortical cataract was reduced for subjects in the highest quintile of vitamin D and total carotenoids and that persons with cataract may have lower levels of vitamin C and higher levels of vitamin B-6 and Se.
作为一项关于营养与老年性白内障关系的探索性研究的一部分，对112名年龄在40至70岁的受试者进行了营养状况生化指标与老年性白内障之间关系的研究。77名受试者至少有一只眼睛患有白内障。测定了血液中总类胡萝卜素、维生素A、维生素D、维生素E、维生素C、核黄素、硫胺素、维生素B-6、锌、铜、硒和镁的水平。将受试者按每种营养素分为五个五分位数组。采用逻辑回归分析来估计最高五分位数组和中间三个五分位数组的受试者相对于最低五分位数组的受试者患白内障的比值比（OR）。OR根据年龄、性别、种族和糖尿病的存在情况进行了调整。结果表明，维生素D和总类胡萝卜素最高五分位数组的受试者皮质性白内障风险降低，且白内障患者的维生素C水平可能较低，维生素B-6和硒水平较高。
