Institut Hospitalo-universitaire Méditerranée Infection, Marseille, France.
Aix Marseille Université, Institut de Recherche pour le Développement (IRD), Assistance Publique-Hôpitaux de Marseille (APHM), Microbes Evolution Phylogénie et Infections (MEPHI), Marseille, France.
J Antimicrob Chemother. 2021 Jun 18;76(7):1655-1657. doi: 10.1093/jac/dkab102.
There is a discrepancy between antibiotic use in medicine and agriculture in the intertropical zone and frequency of antibiotic resistance in clinical bacteria in these countries. We provide evidence that glyphosate (a herbicide but also an antibiotic drug) could be a possible driver of antibiotic resistance in countries where this herbicide is widely used because of modification of the microbial environment. Emergence of resistance in bacteria and fungi is correlated with glyphosate use in the world over the last 40 years.
在热带地区,医学和农业领域的抗生素使用情况与这些国家临床细菌中的抗生素耐药频率存在差异。我们提供的证据表明,由于微生物环境的改变,草甘膦(一种除草剂,但也是一种抗生素药物)可能是导致这些除草剂广泛使用的国家出现抗生素耐药的一个因素。在过去的 40 年中,世界范围内细菌和真菌耐药性的出现与草甘膦的使用有关。