Urata H, Komeda K, Tochigi H, Morishita F, Horiuchi E
Jpn J Antibiot. 1977 Oct;30(10):829-34.
Forty eight patients with urinary tract infections including a case of acute prostatitis were treated with S-6436 and the following results were obtained: 1. Thirty eight patients with acute cystitis resulted in 19 excellent, 15 good and 4 poor with effectiveness rate of 89.5%. 2. Ten patients with complicated urinary tract infections resulted in 1 excellent, 5 good and 4 poor with effectiveness rate of 60%. 3. Infecting organisms from 38 patients with acute cystitis were occupied by 28 strains of E. coli. The sensitivity rate of the infecting organisms to cephalexin was 96.4%. 4. In a few cases (6.25%) side effects of S-6436 were observed. 5. S-6436 will be one of the good first choice antibiotics for acute cystitis.
48例尿路感染患者（包括1例急性前列腺炎患者）接受了S - 6436治疗，结果如下：1. 38例急性膀胱炎患者中，19例疗效极佳，15例良好，4例不佳，有效率为89.5%。2. 10例复杂性尿路感染患者中，1例疗效极佳，5例良好，4例不佳，有效率为60%。3. 38例急性膀胱炎患者的感染菌中，大肠杆菌有28株。感染菌对头孢氨苄的敏感率为96.4%。4. 少数病例（6.25%）观察到了S - 6436的副作用。5. S - 6436将成为急性膀胱炎的优良首选抗生素之一。
